AI Article Synopsis
- * The full-genome sequencing revealed a specific genotype constellation (G9-P[23]-I5-R1-C1-M1-A8-N1-T1-E1-H1), with the non-G/P part showing similarities to strains found in pigs.
- * Phylogenetic analysis suggested that all 11 genes of strain KKL-117 likely originated from porcine rotavirus, highlighting the link between human and pig rotavirus strains.
Article Abstract
An unusual rotavirus strain with the G9P[23] genotype (RVA/Human-wt/THA/KKL-117/2014/G9P[23]) was identified in a stool specimen from a 10-month-old child hospitalized with severe diarrhoea. In this study, we sequenced and characterized the complete genome of strain KKL-117. On full-genomic analysis, strain KKL-117 was found to have the following genotype constellation: G9-P[23]-I5-R1-C1-M1-A8-N1-T1-E1-H1. The non-G/P genotype constellation of this strain (I5-R1-C1-M1-A8-N1-T1-E1-H1) is commonly shared with rotavirus strains from pigs. Furthermore, phylogenetic analysis indicated that each of the 11 genes of strain KKL-117 appeared to be of porcine origin. Our observations provide important insights into the dynamic interactions between human and porcine rotavirus strains.
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| http://dx.doi.org/10.1099/jgv.0.000722 | DOI Listing |
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