Objective: The purpose of this study is to evaluate a new device using molecular breast imaging (MBI) for Tc-sestamibi-guided stereotactic lesion localization as a complementary biopsy tool.
Materials And Methods: From December 2012 to May 2016, a total of 38 consecutive women (mean age, 59 years; range, 41-77 years) underwent Tc-sestamibi-guided biopsy using a new MBI-based device and were retrospectively reviewed. The biopsy modality used five steps: stereotactic localization of the Tc-sestamibi-avid lesion, calculation of coordinates of the lesion location using dedicated software, placement of the needle, verification of the correct needle position, and tissue sampling with a vacuum-assisted device followed by placement of a radiologic marker at the biopsy site and ex vivo measurement of the biopsy specimens.
Results: The procedure was technically successful in all 38 lesions. In all cases, biopsy samples were radioactive and adequate for histopathologic analysis. Nineteen lesions (50%) were found to be malignant, and the remaining lesions were found to be benign. The mean procedure time was 71 minutes (range, 44-112 minutes). The radiologic marker was successfully deployed in 37 lesions (97%). Two hematomas and three vasovagal reactions were observed.
Conclusion: Technetium-99m sestamibi-guided biopsy performed using a dedicated MBI-based device is technically feasible and represents a valuable complementary biopsy tool in breast lesion diagnosis.
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http://dx.doi.org/10.2214/AJR.17.18083 | DOI Listing |
Indian J Pathol Microbiol
March 2025
Department of Radiodiagnosis, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.
Glial choristoma (GC) is a rare developmental malformation commonly occur in nasal cavity and infrequently present at other sites like palate, tongue, pharynx, lips, and submandibular region. It usually occurs in the children either as an incidental finding or mass lesion or in association with cleft palate. GC is diagnosed by the demonstration of glial tissue on histopathology.
View Article and Find Full Text PDFIndian J Pathol Microbiol
March 2025
Department of Obstetrics and Gynecology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, Maharashtra, India.
Dermatofibrosarcoma protuberans (DFSP) is a rare cutaneous mesenchymal locally aggressive sarcoma with high recurrence. We report a case of recurrent vulvar DFSP, and a literature review was performed with a PubMed search using the terms "Dermatofibrosarcoma protuberans" and "vulva." Total 85 cases with vulvar DFSP were analyzed for their clinicopathological features among fibrosarcomatous DFSP (FS-DFSP) and non-FS-DFSP.
View Article and Find Full Text PDFEar Nose Throat J
March 2025
ENT Department and Cervical Surgery Farhat Hached Hospital, Medicine University, Sousse, Tunisia.
A 36-year-old male with a history of smoking presented with recurrent right submandibular swelling. Initially diagnosed with pleomorphic adenoma, he underwent total submandibulectomy. After 2 years, he developed a recurrent submandibular mass.
View Article and Find Full Text PDFTransl Vis Sci Technol
March 2025
Department of Ophthalmology, Guangdong Eye Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Purpose: We aimed to analyze retinal neurovascular unit (RNVU) alterations and function via optical coherence tomography angiography (OCTA) and full-field electroretinography (ERG) in patients with ischemic stroke (IS).
Methods: OCTA was used to measure RNVU changes in 229 participants (101 with IS and 128 healthy controls). The RETeval device was used to record full-field electroretinograms (FERGs) in 40 participants (14 with IS and 26 healthy controls).
J Contemp Dent Pract
December 2024
Department of Conservative Dentistry and Endodontics, DA Pandu Memorial RV Dental College, Bengaluru, Karnataka, India, Orcid: https://orcid.org/0009-0002-8185-3912.
Aim: Bioceramic sealers are being used as obturation materials as they are known for hard tissue induction and facilitating periapical healing. Based on some studies, one can hypothesize that mineral trioxide aggregate (MTA) and biodentine used as the sole obturating material could reinforce the tooth and provide a better sealability than an MTA/biodentine apical plug with gutta-percha obturation. However, there are not many high-quality studies regarding outcomes of complete MTA/biodentine obturations compared with traditional obturation methods.
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