Intramedullary spinal tuberculoma is an extremely rare disease when compared to pulmonary, extrapulmonary and skeletal tuberculosis in developing countries. In the absence of systemic tuberculosis, clinical presentation is non distinctive from other intramedullary lesions. We report two cases of intramedullary tuberculoma both presenting with signs and symptoms of space occupying lesions. Surgical excision was done in both cases following which patients improved neurologically. Histopathological evaluation is essential to provide curative treatment.
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http://dx.doi.org/10.14444/4002 | DOI Listing |
J West Afr Coll Surg
March 2023
Department of Anatomic Pathology and Forensic Medicine, Jos University Teaching Hospital, Jos, Nigeria.
Background And Objective: Intramedullary tuberculoma (IMT) of the conus medullaris is an extremely rare tumour that constitutes a diagnostic and management challenge in a resource-limited setting. We report a case of conus medullaris, IMT in a young immunocompetent, patient with no prior clinical features of pulmonary or extra-pulmonary tuberculosis.
Case Summary: The patient presented with six months history of progressive and persistent mid back pain and slight weakness of both lower limbs of 3 months duration.
Cureus
March 2020
Internal Medicine, The University of Texas Health Science Center/Christus Good Shepherd Medical Center, Longview, USA.
Central nervous system (CNS) tuberculosis (TB), caused by Mycobacterium tuberculosis (MT), is a severe form of TB, which presents as meningitis, cerebritis, abscesses, spinal tuberculous arachnoiditis, and rarely tuberculomas. CNS TB is prevalent in the underdeveloped or developing world and is common in malnourished, alcoholics, children, young adults, immunocompromised, and cancer patients. Intracranial tuberculomas (ICT) can present with symptoms and signs of focal neurological deficits with or without systemic manifestations.
View Article and Find Full Text PDFAsian J Neurosurg
January 2017
Department of Neurosurgery, Achanta Lakshmipathi Neurosurgical Centre, Voluntary Health Services, Taramani, Chennai, Tamil Nadu, India.
Disseminated tuberculomas in the brain and spinal cord are rare. To the best of our knowledge, only nine cases of spinal intra-medullary tuberculomas with cranial involvement have been reported till date. However, involvement of all levels in the spinal cord, brain stem with pan lobar involvement of the cerebrum and cerebellum has not been reported so far.
View Article and Find Full Text PDFInt J Spine Surg
January 2017
Department of Neurosurgery, Jawaharlal Nehru Medical College, Nehru Nagar, India.
Intramedullary spinal tuberculoma is an extremely rare disease when compared to pulmonary, extrapulmonary and skeletal tuberculosis in developing countries. In the absence of systemic tuberculosis, clinical presentation is non distinctive from other intramedullary lesions. We report two cases of intramedullary tuberculoma both presenting with signs and symptoms of space occupying lesions.
View Article and Find Full Text PDFJ Med Case Rep
November 2012
Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Introduction: Intra-medullary spinal tuberculoma is a rare form of tuberculosis, with an incidence of only two in 100,000 patients with tuberculosis. We present a case of intra-medullary tuberculoma from Pakistan, which was diagnosed by radiological findings and analysis of cerebrospinal fluid using polymerase chain reaction testing.
Case Presentation: We present the case of a 28-year-old Sindhi male with intra-medullary tuberculoma of the spinal cord at the C3 level.
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