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Shift work schedules alter immune cell regulation and accelerate cognitive impairment during aging.
J Neuroinflammation
January 2025
Department of Neuroscience and Experimental Therapeutics, School of Medicine, Texas A&M Health Science Center, Bryan, TX, 77807-3260, USA.
Background: Disturbances of the sleep-wake cycle and other circadian rhythms typically precede the age-related deficits in learning and memory, suggesting that these alterations in circadian timekeeping may contribute to the progressive cognitive decline during aging. The present study examined the role of immune cell activation and inflammation in the link between circadian rhythm dysregulation and cognitive impairment in aging.
Methods: C57Bl/6J mice were exposed to shifted light-dark (LD) cycles (12 h advance/5d) during early adulthood (from ≈ 4-6mo) or continuously to a "fixed" LD12:12 schedule.
Iatrogenic intramural esophageal hematoma during EUS-B-FNA procedure.
BMC Pulm Med
January 2025
Unidade de Broncologia e Pneumologia de Intervenção - Instituto Português de Oncologia Francisco Gentil, Coimbra, Portugal.
Background: Esophageal ultrasound with bronchoscope fine needle aspiration (EUS-B-FNA) is a valuable tool for the diagnosis and staging of lung cancer, complementing endobronchial lung ultrasound (EBUS). While generally considered safe, there is a notable lack of comprehensive knowledge within the interventional pulmonology community regarding potential complications.
Case Presentation: We present a case involving a 66-year-old male with squamous cell lung carcinoma undergoing mediastinal staging.
Left-handed use of surgical instruments: improved function through understanding instrument design.
J Am Vet Med Assoc
January 2025
Objective: To explain design features of scissors and surgical instruments that work against left-handed users and demonstrate how the user can adapt their technique for ambidextrous use of standard instruments.
Animals: Any species.
Methods: Standard instruments are designed for maximal efficiency with the use of a right-handed grip.
Research Progress on the Posterior Midline Lumbar Spinous Process-Splitting Approach.
Orthop Surg
January 2025
Health Science Center, Ningbo University, Ningbo, China.
The traditional posterior median approach laminectomy is widely used for lumbar decompression. However, the bilateral dissection of paraspinal muscles during this procedure often leads to postoperative muscle atrophy, chronic low back pain, and other complications. The posterior midline spinous process-splitting approach (SPSA) offers a significant advantage over the traditional approach by minimizing damage to the paraspinal muscles.
View Article and Find Full Text PDFA Surgical Technique Guide for Percutaneous Screw Fixation for Metastatic Pelvic Lesions.
JBJS Essent Surg Tech
January 2025
Department of Orthopaedic Surgery, Montefiore Medical Center, Bronx, New York.
Background: The pelvis is one of the most common areas for metastatic bone disease. We recently described the use of a minimally invasive percutaneous screw fixation of metastatic non-periacetabular pelvic lesions, with excellent results.
Description: The procedure can be completed in a standard operating theater without the need for special instruments.
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