Video-assisted thoracoscopy in the management of intrapleural extravasation of cytotoxic chemotherapy.

Thorac Cancer

Cardiothoracic Surgical Unit, Department of Cardiothoracic Surgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia.

Published: July 2017

The extravasation of cytotoxic agents into subcutaneous tissue is a serious complication of chemotherapy. Unfortunately, if such extravasation occurs into the pleural space, limited data is available to guide appropriate management. We present the first report in the literature of video-assisted thoracoscopy combined with a topoisomerase II inhibitor and iron chelator, dexrazoxane, in the successful management of this complication.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494449PMC
http://dx.doi.org/10.1111/1759-7714.12430DOI Listing

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