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Use of Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography for Nodal Staging in Prostate Cancer and Tailoring of Treatment: A Continuing Conundrum.
Eur Urol
December 2024
Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Trials have shown that prostate-specific membrane antigen (PSMA)-based positron emission tomography/computed tomography (PET/CT) is more accurate than conventional imaging for staging of nodal status in prostate cancer. We discuss the advantages of PSMA PET/CT over current options for nodal staging and highlight the issues that need to be resolved for implementation of this modality in routine practice.
View Article and Find Full Text PDFSudden Unexpected Death-COVID-19, Cardiac Rhythm or Conundrum?
Heart Lung Circ
December 2024
University of Melbourne, Parkville Vic, Australia; St Vincent's Institute of Medical Research, Fitzroy, Vic, Australia; Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia.
Introduction: Deregulation of the cerebrovascular system has been linked to neurodegeneration, part of a putative causal pathway into etiologies such as Alzheimer's disease (AD). In medical imaging, time-of-flight magnetic resonance angiography (TOF-MRA) and perfusion MRI are the most common modalities used to study this system. However, due to lack of resources, many large-scale studies of AD are not acquiring these images; this creates a conundrum, as the lack of evidence limits our knowledge of the interaction between the cerebrovascular system and AD.
View Article and Find Full Text PDFThe Conundrum of Preterm Labour and Premature Births in Present Day Obstetrics.
J Obstet Gynaecol India
October 2024
Nowrosjee Wadia Maternity Hospital, Mumbai, India.
Preterm Labour leading to premature births has remained one of the longest unresolved conundrums in medicine. This "conundrum" of issues surrounding preterm labour and birth appears to be complex. While we continue to accept that preterm birth is difficult to predict, we are being faced with an increasing trend in preterm births owing to the preponderance of the known risk factors in the present day Obstetric population.
View Article and Find Full Text PDFCuff Conundrums: Best Practice Recommendations for Urethral Instrumentation With an Artificial Urinary Sphincter in Place.
J Urol
November 2024
Department of Urology, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
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