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http://dx.doi.org/10.1111/trf.14100 | DOI Listing |
Purpose Of The Study: Intraarticular fractures of the distal femur rank among the most severe musculoskeletal injuries. Various treatment options, such as plate osteosynthesis or retrograde nailing, can be employed. This study aims to evaluate the clinical outcomes and complications of intraarticular distal femoral fractures treated with retrograde femoral nail, with particular emphasis on C3 fractures.
View Article and Find Full Text PDFBiology (Basel)
November 2024
Institute of Biomedical Chemistry, 109028 Moscow, Russia.
Biobanks are involved in a broad range of studies, including both basic and clinical research, so their functions and roles are evolving. Digital biobanks have emerged due to digitalization in this field; however, it also entails an increasing number of ethical and legal issues, in particular those related to the protection of donor data and potential commercial applications. The development of biobanks and the size of stored datasets lay the groundwork for proceeding to digital biobanks that intensely employ artificial intelligence tools.
View Article and Find Full Text PDFBMC Med Educ
January 2025
University of Birmingham, Birmingham, United Kingdom.
Purpose: Free Open Access Medical Education (FOAMed) is an emergent phenomenon within medical education. The rise of FOAMed resources has meant that medical education needs no longer be confined to the lecture theatre or the hospital setting, but rather, can be produced and shared amongst any individual or group with access to internet and a suitable device. This study presents a review of the use of FOAMed resources by students as part of their university medical education.
View Article and Find Full Text PDFJCO Oncol Pract
December 2024
Medical Oncology, Yale Cancer Center, Yale University, New Haven, CT.
Purpose: Cyclin-dependent kinase 4/6 inhibitors (CDK4/6is) combined with endocrine therapy (ET) are the standard of care in hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced breast cancer (aBC). Yet, disease progression remains common. In the absence of established postprogression sequencing guidelines, we conducted a pooled analysis of Kaplan-Meier (KM)-derived patient data to assess the efficacy of subsequent treatment options after disease progression on CDK4/6i therapy.
View Article and Find Full Text PDFProbl Sotsialnoi Gig Zdravookhranenniiai Istor Med
November 2024
The Federal State Budget Institution "The Central Research Institute for Health Organization and Informatics" of Minzdrav of Russia, 127254, Moscow, Russia,
The population morbidity is one of leading indicators of public health. On the basis of morbidity, not only population needs in various types of medical care are determined, but also development of medical organizations network is prognosticated and effectiveness of health care system is assessed. This approach permits to adjust functioning of population medical care services in each Subject of the Russian Federation.
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