Small cell carcinoma of the ovary hypercalcemic type (SCCOHT): A rare case after in vitro fertilization (IVF).

Pak J Med Sci

Nikita Islam, MBBS, MD, MRCOG. Department of Gyne Oncology, King Abdullah Medical City (KAMC-HC), Makkah, Saudi Arabia.

Published: January 2017

Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a very rare and lethal tumor, mostly affecting young women, with aggressive clinical course. It has a worse prognosis in younger women and most of them died within two years of diagnosis. We are reporting a unique case of SCCOHT in a 35 years old, nulliparous lady with primary infertility in which symptomatic hypercalcemia was a presenting feature of her cancer. She was completely healthy before third cycle of IVF. Within two months of her third IVF cycle, she developed SCCOHT with a very rapid and aggressive course of disease and fatal outcome. Patient died within one month of her first symptom presentation (3 months after IVF cycle).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368318PMC
http://dx.doi.org/10.12669/pjms.331.11634DOI Listing

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