Clinical outcomes of switching from insulin glargine to NPH insulin in indigent patients at a charitable pharmacy: The Charitable Insulin NPH: Care for the Indigent study.

Objectives: To assess the clinical outcomes of indigent patients with type 2 diabetes served by a charitable pharmacy after therapy change from insulin glargine to NPH insulin.

Design: This was a 24-week prospective pilot study.

Setting: Community charitable pharmacy.

Participants: Underserved, financially disadvantaged adults with type 2 diabetes.

Intervention: Conversion from insulin glargine to NPH insulin.

Main Outcome Measures: HbA, 30-day average blood glucose, number of suspected and confirmed hypoglycemic episodes, total insulin dose, and Morisky Medication Adherence Scale (MMAS) scores.

Results: Patients in both control and intervention groups improved in disease-state clinical markers, safety profile, and total insulin dose. MMAS scores were unchanged.

Conclusion: There were no statistically significant differences in glycemic control or hypoglycemic episodes between the control (NPH insulin) or intervention group (insulin glargine to NPH insulin).