Division of Allergy and Clinical Immunology, University of Texas Medical Branch, 4.116 JSA, 301 University Boulevard, Galveston, TX 77555-0568, USA. Electronic address:
Published: May 2017
AI Article Synopsis
Article Abstract
Chronic obstructive pulmonary disease (COPD) is common worldwide. The predominant cause in most COPD is environmental exposure to toxicants. The inflammatory processes in COPD are multifactorial, complex, and interacting, leading to many potential therapeutic targets. Although most typically associated with neutrophilic/macrophagic inflammation (type 1), it is now known that COPD can also be associated with eosinophilic inflammation (type 2), particularly in exacerbations. Accordingly, there is an active program of investigation of highly selective biologic therapeutic agents in the management of COPD. This review summarizes clinical trials of the use of these novel agents in the management of COPD.
Department of Biostatistics and Epidemiology, Hudson College of Public Health, University of Oklahoma Health Sciences, Oklahoma City, OK, United States.
Background: Chronic Obstructive Pulmonary Disease (COPD), mainly caused by cigarette smoking, is one of the leading causes of death in the United States (US) and frequent asthma attacks are often exacerbated by cigarette use. Electronic cigarettes (e-cigarettes) are often used to quit cigarette smoking. Prevalence of COPD, asthma, cigarette use, and e-cigarette use differs between racial/ethnic groups.
Background: Cardiovascular health (CVH) assessment may have important benefits for adults with chronic diseases to prevent incident cardiovascular disease and additional chronic conditions. Few studies have compared CVH in adults with chronic diseases and healthy adults without chronic disease using the American Heart Association's (AHA's) Life's Essential 8 (LE8) metrics.
Methods And Results: We used National Health and Nutrition Examination Survey data from 2013 to 2018 to identify the presence of 16 chronic diseases by participant self-report of diagnosis.
Chronic obstructive pulmonary disease (COPD) is a type of lung disease marked by permanent damage to tissues in the lungs. Over time, chronic obstructive pulmonary disease (COPD) can make breathing difficult due to permanent lung damage. COPD encompasses two main conditions chronic bronchitis, where inflammation and scarring narrow the large airways, and emphysema, where the tiny air sacs in the lungs are damaged.
