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Successful Laparoscopy-Assisted Extirpation of Burkitt's Lymphoma Causing Intestinal Obstruction in a 17-Year-Old Boy.
J Clin Med
December 2024
Department of Pediatric Surgery and Orthopedics, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540142 Târgu Mureș, Romania.
Childhood extranodal B-cell non-Hodgkin's lymphomas are often caused by Burkitt's lymphoma (BL). Treatment usually involves intensive polychemotherapy, and recent prospective trials show significantly improved outcomes. Surgery primarily involves conducting biopsies; ablative interventions are not recommended.
View Article and Find Full Text PDFCase Report: Acute intussusception in a 2-year-old male patient: a rare case of Burkitt's lymphoma coexisting with Meckel's diverticulum.
Front Pediatr
December 2024
Department of Gastrointestinal Surgery, The First People's Hospital of Wuhu, Anhui, China.
In children, 90% cases of intussusception are idiopathic and the remaining 10% are attributed to underlying diseases (most commonly due to Meckel's diverticulum, polyps then either duplication cyst or mesentery cysts, and rarely due to Burkitt's lymphoma). The occurrence of acute intestinal intussusception caused by Burkitt's lymphoma in children under the age of 5 is exceedingly rare. Burkitt's lymphoma presents with diverse clinical manifestations, often leading to the identification of an abdominal tumor in pediatric patients.
View Article and Find Full Text PDFSurvival of HIV associated diffuse large B-cell lymphoma and Burkitt lymphoma in China.
Sci Rep
December 2024
Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, 169 Donghu Road, Wuhan, 430071, China.
Article Synopsis
- Combination antiretroviral therapy (ART) has significantly improved the treatment outcomes for patients with HIV-associated non-Hodgkin lymphoma, specifically Burkitt lymphoma and diffuse large B-cell lymphoma, based on a study of 127 patients treated over 17 years.
- The study found that DA-EPOCH ± R was the most common therapy for HIV-BL, while CHOP± R was used for HIV-DLBCL, with complete response rates of 36% and 44%, respectively.
- Despite these advancements, challenges remain in treating HIV-related lymphomas in China due to low rates of pre-diagnosis ART, high patient morbidity, and late-stage diagnoses.
Burkitt's lymphoma with multi-organ involvement.
Int J Surg Case Rep
December 2024
Department of Pathology, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Article Synopsis
- Burkitt's lymphoma (BL) is a fast-growing B-cell non-Hodgkin lymphoma that often affects multiple organs, including rare cases in the gastrointestinal tract, which makes up less than 2% of small intestinal cancers.!* -
- A 34-year-old man with sickle cell trait showed symptoms like abdominal pain and weight loss, and after imaging and surgery, he was diagnosed with Burkitt's lymphoma that affected his cecum, appendix, peritoneum, and bone marrow.!* -
- The case emphasizes the significance of recognizing the fast progression of BL and the "starry sky" pattern in histopathology for accurate diagnosis and correlation in clinical settings.!*
Localized large B-cell lymphoma with MYC and BCL6 rearrangements as an unexpected finding in an appendectomy specimen.
APMIS
January 2025
Department of Pathology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
Large B-cell lymphomas (LBLs) comprise a genetically heterogeneous group of clinically aggressive non-Hodgkin lymphomas, frequently exhibiting overlapping features with diffuse large B-cell lymphoma and Burkitt's lymphoma. We report a case of a 24-year-old, previously healthy male with a classical clinical presentation of acute appendicitis. The pathologic examination discovered a large B-cell lymphoma with MYC and BCL6 rearrangements in the excised appendix.
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