Background: Studies examining patient-reported outcomes in subjects with vestibular schwannoma (VS) and "excellent" hearing are lacking.
Objective: To assess patient-reported audiovestibular handicap and overall quality of life (QoL) in VS patients with class A hearing in both ears.
Methods: Among 539 VS patients treated during 1998 to 2008, we identified 296 patients with either bilateral class A (AA) hearing or 1 good ear and 1 deaf ear (AD) according to the American Academy of Otolaryngology-Head and Neck Surgery classification. Patients responded to validated hearing, tinnitus, and dizziness handicap inventories and 2 QoL questionnaires, and the 2 groups were compared. A reference group of 103 adults filled out the same questionnaires.
Results: Forty-nine patients (16.6%) had class AA and 247 patients (83.4%) had class AD hearing. AA patients scored poorer than control subjects without tumor on all handicap questionnaires ( P < .001) and a VS-specific QoL instrument ( P = .006). Con-versely, AA patients scored significantly better than patients with AD on the hearing inventory and the disease-specific QoL instrument ( P < .001), but no difference was found between these groups with regard to tinnitus and dizziness. The hearing disability score was approximately 3 times poorer for AA patients compared with control subjects without tumor; a third of AA patients reported a hearing handicap.
Conclusion: Patients with VS and bilateral class A hearing report significantly poorer hearing handicap than control subjects without tumor but better hearing than those with unilateral deafness. When patients with bilateral class A hearing are counseled, it should be noted that one-third of patients experience self-perceived hearing handicap.
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http://dx.doi.org/10.1227/NEU.0000000000001238 | DOI Listing |
Otol Neurotol
February 2025
Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Background Introduction: Vestibular schwannoma (VS) tumors typically present with sensorineural hearing loss (SNHL). Losartan has recently demonstrated prevention of tumor-associated SNHL in a mouse model of VS through suppression of inflammatory and pro-fibrotic factors, and the current study investigates this association in humans.
Methods: This is a retrospective study of patients with unilateral VS and hypertension followed with sequential audiometry at a tertiary referral hospital from January 1994 to June 2023.
J Family Med Prim Care
December 2024
Retired Assistant Research Officer, Department of Occupational Health, All India Institute of Hygiene and Public Health, Kolkata, West Bengal, India.
Introduction: Workers who work in metallurgy factories processing aluminium are at risk of exposure to various kinds of metals and chemicals.
Objective: To describe sociodemographic characteristics and to find out morbidity profile of study participants .
Methods: A cross-sectional O bservational descriptive study was conducted in two aluminium processing metallurgy factories in Howrah district of Indian state of West Bengal.
Zhonghua Nei Ke Za Zhi
January 2025
Department of Endocrinology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou570311, China.
Children (Basel)
November 2024
Oto-Rhino-Laryngology Surgery Clinic, World Hearing Center, Institute of Physiology and Pathology of Hearing, 02-042 Warsaw, Poland.
Background/objectives: The aim of the study was to evaluate the prevalence of undiagnosed hearing impairment or central auditory processing disorders in children from I and VIII grades of primary schools in Warsaw.
Methods: The participants in the study were 15,659 pupils from classes I and VIII attending primary schools in Warsaw. As part of the study, the hearing threshold for air conduction at frequencies of 0.
Int J Surg Case Rep
January 2025
Department of Otolaryngology-Head and Neck Surgery, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Introduction: Glomus tympanicum is a benign tumor classified under the group glomus tumors, and is also known as paragangliomas.
Case Presentation: A 52 years old woman presented with unilateral pulsatile tinnitus and hearing loss. She had a visible reddish mass behind the eardrum; Temporal bone CT scans suggested middle ear mass secondary to Glomus Tympanicum tumors.
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