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http://dx.doi.org/10.5152/npa.2015.12363 | DOI Listing |
Nephrol Nurs J
January 2025
Director, the Marian K. Shaughnessy Nurse Leadership Academy.
Nephrology nurses working in hemodialysis units face unique challenges managing multiple patients - an experience often contributing to higher levels of burnout and stress, and potentially lower job satisfaction and retention rates, exacerbating the existing nursing shortage in dialysis settings. Targeted strategies are essential to improve job satisfaction. In this study, we explored the relationship between emotional intelligence and job satisfaction among nephrology nurses working in acute and chronic hemodialysis settings.
View Article and Find Full Text PDFJ Neurosci Res
January 2025
Department of Psychology, University of Regensburg, Regensburg, Germany.
Anxiety and depression disorders show high prevalence rates, and stress is a significant risk factor for both. However, studies investigating the interplay between anxiety, depression, and stress regulation in the brain are scarce. The present manuscript included 124 law students from the LawSTRESS project.
View Article and Find Full Text PDFJ Med Chem
January 2025
Department of Chemical Biology, Helmholtz Centre for Infection Research, Inhoffenstr. 7, Braunschweig 38124, Germany.
The main protease M is a clinically validated target to treat infections by the coronavirus SARS-CoV-2. Among the first reported M inhibitors was the peptidomimetic α-ketoamide , whose cocrystal structure with M paved the way for multiple lead-finding studies. We established structure-activity relationships for the series by modifying residues at the P1', P3, and P4 sites.
View Article and Find Full Text PDFMicrobiol Spectr
January 2025
Department of Pharmacology, Showa University Graduate School of Medicine, Shinagawa, Tokyo, Japan.
Unlabelled: The concept of genome-microbiome interactions, in which the microenvironment determined by host genetic polymorphisms regulates the local microbiota, is important in the pathogenesis of human disease. In otolaryngology, the resident bacterial microbiota is reportedly altered in non-infectious ear diseases, such as otitis media pearls and exudative otitis media. We hypothesized that a single-nucleotide polymorphism in the ATP-binding cassette sub-family C member 11 () gene, which determines earwax properties, regulates the ear canal microbiota.
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