Background: The myocardial performance index (MPI) first described by Chuwa Tei in 1995 is a relatively new echocardiographic variable used for assessment of overall cardiac function. Previous studies have demonstrated the MPI to be a sum representation of both left ventricular systolic and diastolic function with prognostic value in patients with coronary artery disease as well as symptomatic heart failure.
Methods: Ninety patients with either established coronary artery disease (CAD) or CAD risk factors underwent routine treadmill exercise stress testing with two-dimensional Doppler echocardiography using the standard Bruce protocol. Both resting and stress MPI values were measured for all 90 of the patients.
Results: Using a normal MPI cut off of ≤ 0.47, the prevalence of an abnormal resting MPI in our 90 subjects was 72/90 or 80% and the prevalence of an abnormal stress MPI in our 90 subjects was 48/90 or 53.33%. The average MPI observed in the resting portion of the stress test for the cohort was: 0.636 with a standard deviation of 0.182. The average MPI in the stress portion of the stress test for the cohort was 0.530 with a standard deviation of 0.250. The P value with the use of a one-tailed dependent T test was calculated to be < 0.05.
Conclusion: We postulate that these findings reflect that the MPI (Tei) index assessed during exercise may be a sensitive indicator of occult coronary disease in an at risk group independent of wall motion assessment.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358305 | PMC |
| http://dx.doi.org/10.4021/cr296w | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Physical and rheological properties of agglomerated milk protein isolate-guar gum mixtures: effect of binder type and concentration.
Food Sci Biotechnol
January 2025
Department of Food Science and Biotechnology, Dongguk University-Seoul, 32 Dongguk-ro, Ilsandong-gu, Goyang, 10326 Gyeonggi Korea.
Unlabelled: Our study sought to investigate how the fluidized-bed agglomeration process, incorporating sugar and sugar alcohol binders, affects the physical and rheological properties of milk protein isolate (MPI)-guar gum (GG) mixtures. The agglomerated MPI-GG mixtures (AMGs) consisted of larger and more porous particles with a uniform particle size distribution and showed better solubility compared to non-agglomerated MG (NMG). Additionally, the agglomeration process with binders improved powder flowability by reducing powder cohesion.
View Article and Find Full Text PDFDo We Need to Reconsider How We Gauge Success After Anatomic Total Shoulder Arthroplasty? A Study of Thresholds Optimized for Patient Satisfaction Using the Simple Shoulder Test.
J Shoulder Elbow Surg
January 2025
Department of Orthopaedic Surgery and Sports Medicine, University of Washington Medical Center, 1959 NE Pacific Street, Box 356500, Seattle, WA 98195-6500. Electronic address:
Background: Clinically important improvement after total shoulder arthroplasty is often assessed with shoulder-specific patient-reported outcome measures (PROMs) quantifying reduction in pain and restoration in function. It is unclear if commonly utilized threshold such as minimal clinically important difference (MCID), substantial clinical benefit (SCB), or patient acceptable symptom state (PASS), represent optimal improvement from the patients' perspective. The objectives of this study were to utilize the Simple Shoulder Test to: 1) compare commonly utilized thresholds for change in score and final score to thresholds optimized to patient satisfaction using receiver operative characteristic (ROC) curve analysis, and 2) determine the impact of using different thresholds on reporting of independent predictors of successful outcome in terms of patient satisfaction.
View Article and Find Full Text PDFObjective: ADHD is one of the most common neurodevelopmental disorders, seen in children and adolescents, and is often treated with various pharmacological agents, especially methylphenidate. There are differing opinions in the literature regarding the cardiovascular safety of long-term methylphenidate use. Studies suggest that the drug may increase the risk of hypertension, myocardial infarction, ventricular arrhythmia, sudden cardiac death, cardiomyopathy, heart failure (HF), pulmonary hypertension, and stroke.
View Article and Find Full Text PDFFerrimagnetic Heusler tunnel junctions with fast spin-transfer torque switching enabled by low magnetization.
Nat Nanotechnol
January 2025
Max Planck Institute for Microstructure Physics, Halle (Saale), Germany.
Magnetic random-access memory that uses magnetic tunnel junction memory cells is a high-performance, non-volatile memory technology that goes beyond traditional charge-based memories. Today, its speed is limited by the high magnetization of the memory storage layer. Here we prepare magnetic tunnel junction memory devices with a low magnetization ferrimagnetic Heusler alloy MnGe as the memory storage layer on technologically relevant amorphous substrates using a combination of a nitride seed layer and a chemical templating layer.
View Article and Find Full Text PDFAn L-plug-and-play approach for MPI using a zero shot denoiser with evaluation on the 3D open MPI dataset.
Phys Med Biol
January 2025
Faculty of Mathematics and Natural Sciences , Hochschule Darmstadt, Schöfferstr., 3, Darmstadt, Hessen, 64295, GERMANY.
Magnetic Particle Imaging (MPI) is an emerging medical imaging modality which has gained increasing interest in recent years. Among the benefits of MPI are its high temporal resolution, and that the technique does not expose the specimen to any kind of ionizing radiation. It is based on the non-linear response of magnetic nanoparticles to an applied magnetic field.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!