AI Article Synopsis
- - The study aimed to explore the relationship between specific genetic markers and metabolic syndromes like dyslipidemia, obesity, and type 2 diabetes in a Northeastern Mexican population.
- - Researchers analyzed 37 families, focusing on 63 specific single nucleotide polymorphisms (SNPs) and assessing factors like age, BMI, glucose tolerance, and blood lipid levels.
- - Four genetic markers were linked to these conditions: rs5210 (associated with T2DM), rs11196175 (linked to BMI and cholesterol/LDL levels), rs12255372 (connected to BMI and HDL/VLDL/triglyceride levels), and rs1885088 (related to LDL levels), all showing significant associations (
Article Abstract
The aim of the present study was to investigate whether genetic markers considered risk factors for metabolic syndromes, including dyslipidemia, obesity and type 2 diabetes mellitus (T2DM), can be applied to a Northeastern Mexican population. A total of 37 families were analyzed for 63 single nucleotide polymorphisms (SNPs), and the age, body mass index (BMI), glucose tolerance values and blood lipid levels, including those of cholesterol, low-density lipoprotein (LDL), very LDL (VLDL), high-density lipoprotein (HDL) and triglycerides were evaluated. Three genetic markers previously associated with metabolic syndromes were identified in the sample population, including and . The SNP rs5210 was associated with T2DM, the SNP rs11196175 was associated with BMI and cholesterol and LDL levels, the SNP rs12255372 was associated with BMI and HDL, VLDL and triglyceride levels, and the SNP rs1885088 was associated with LDL levels (P<0.05).
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348709 | PMC |
| http://dx.doi.org/10.3892/etm.2016.3990 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!