AI Article Synopsis
- Chronic wasting disease (CWD) is a prion disease affecting deer, elk, moose, and recently discovered in wild reindeer in Norway, posing a risk to caribou in areas like Alberta, Canada.
- Research focused on the prion protein gene (Prnp) in woodland caribou, revealing a higher frequency of the 138N allele in one population (Chinchaga), which is linked to lower susceptibility to CWD.
- These findings are important for creating management strategies to protect threatened caribou populations from the spread of CWD.
Article Abstract
Chronic wasting disease (CWD) is a prion disease found in deer, elk and moose in North America and since recently, wild reindeer in Norway. Caribou are at-risk to encounter CWD in areas such as Alberta, Canada, where the disease spreads toward caribou habitats. CWD susceptibility is modulated by species-specific polymorphisms in the prion protein gene (Prnp). We sequenced Prnp of woodland caribou from 9 Albertan populations. In one population (Chinchaga) a significantly higher frequency of the 138N allele linked to reduced CWD susceptibility was observed. These data are relevant for developing CWD management strategies including conservation of threatened caribou populations.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399904 | PMC |
| http://dx.doi.org/10.1080/19336896.2017.1300741 | DOI Listing |
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