We report the unexpected formation of a 1-azadiene dimer from 4,6-diphenyl-3,6-dihydro-2-1,3-thiazine-2-thiones under prolonged microwave irradiation. In this manner, thiazine-2-thiones act as "masked" 1-azadiene equivalents, which makes them useful synthetic tools to access complex heterocyclic frameworks. We compare this dimerization with earlier approaches and elaborate on the observed diastereoselectivity.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154663 | PMC |
| http://dx.doi.org/10.3390/molecules22040541 | DOI Listing |
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