Aims: A prospective observational study was conducted in Royal Marines (RM) recruits to investigate throat carriage of group A Streptococcus (GAS) and incidence of soft tissue infections.
Methods: 1012 RM recruits were followed through a 32-week training programme, with throat swabs being obtained in weeks 1, 6, 15, and 32. Alongside a separate cohort of 46 RM Young Officers (YO) undergoing training were sampled in parallel.
Results: Carriage of group A Streptococcus was detected in only 5/1012 (0.49%) recruits at the beginning of training and remained low throughout training. There was no association between GAS carriage and development of soft tissue infection. There was no carriage of GAS in the smaller YO cohort at the start of training, (0/46). At week 6, a surge in GAS carriage was detected in 8/46 (17%) YO, that could be ascribed to a cluster of GAS genotype emm83.
Conclusions: Asymptomatic GAS carriage is very infrequent among young adults in England and this should be borne in mind when considering the relevance of a positive throat swab result in symptomatic patients or outbreaks. Despite low prevalence, there is however potential for GAS to rapidly and transiently disseminate among adults during outbreaks.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jinf.2017.03.001 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Clinical Snapshot of Group A Streptococcal Isolates from an Australian Tertiary Hospital.
Pathogens
November 2024
Australian Infectious Diseases Research Centre, Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4067, Australia.
(Group A , GAS) is a human-restricted pathogen that causes a wide range of diseases from pharyngitis and scarlet fever to more severe, invasive infections such as necrotising fasciitis and streptococcal toxic shock syndrome. There has been a global increase in both scarlet fever and invasive infections during the COVID-19 post-pandemic period. The aim of this study was the molecular characterisation of 17 invasive and non-invasive clinical non-1 GAS isolates from an Australian tertiary hospital collected between 2021 and 2022.
View Article and Find Full Text PDFImpact of COVID-19 health precautions on asymptomatic Streptococcus pyogenes carriage in palestinian children: a pre- and post-pandemic study.
BMC Infect Dis
October 2024
Faculty of Medicine, Al-Quds University, Abu Dis, Palestine.
Article Synopsis
- A study investigated the impact of COVID-19 health measures on the prevalence of asymptomatic Streptococcus pyogenes (GAS) carriage among schoolchildren in the southern West Bank, Palestine, comparing data from before and after the pandemic.
- Results showed a significant decline in GAS carriage from 15.7% pre-COVID-19 to 10.4% post-COVID-19, particularly among urban and medium socioeconomic children.
- Protective factors against GAS carriage included frequent hand washing and tooth brushing, while a higher BMI was identified as a risk factor.
Invasive Streptococcus pyogenes infection: a case report.
Access Microbiol
July 2024
Department of Clinical Bacteriology, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.
Article Synopsis
- - Group A Streptococcus (GAS) is a bacteria that can cause a range of infections, from mild issues like tonsillitis to severe ones like septicemia, and has seen a resurgence in severe cases since the 1980s.
- - A case study describes a 28-year-old man in Morocco who developed septic arthritis after experiencing flu-like symptoms and tonsillitis, leading to significant swelling and joint pain.
- - Treatment involved dual antibiotics and drainage of an abscessed knee joint, highlighting the importance of prompt detection and treatment of severe GAS infections, along with advocating for antibiotic prophylaxis recommendations.
Drinker driver flyer diver.
Diving Hyperb Med
June 2024
Clinical Hyperbaric Facility, Hull and East Riding Hospital, Anlaby, UK.
Blood alcohol concentrations above defined levels are detrimental to cognitive performance. Empirical and published evidence suggest that nitrogen narcosis is analogous to alcohol intoxication with both impairing prefrontal cortex function. Nitrogen narcosis is also known to have been a factor in fatal accidents.
View Article and Find Full Text PDFHeat stress increases carbohydrate oxidation rates and oxygen uptake during prolonged load carriage exercise.
Temperature (Austin)
March 2024
Center for Research & Education in Special Environments, University at Buffalo, Buffalo, USA.
Military missions are conducted in a multitude of environments including heat and may involve walking under load following severe exertion, the metabolic demands of which may have nutritional implications for fueling and recovery planning. Ten males equipped a military pack loaded to 30% of their body mass and walked in 20°C/40% relative humidity (RH) (TEMP) or 37°C/20% RH (HOT) either continuously (CW) for 90 min at the first ventilatory threshold or mixed walking (MW) with unloaded running intervals above the second ventilatory threshold between min 35 and 55 of the 90 min bout. Pulmonary gas, thermoregulatory, and cardiovascular variables were analyzed following running intervals.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!