AI Article Synopsis

  • OPPIDUM (Observation of illegal drugs and misuse of psychotropic medications) is a surveillance system that anonymously gathers data on drug abuse and dependence from patients in specialized care centers for drug dependence, with a focus on assessing real-life drug abuse patterns.
  • In 2015, the system surveyed 5,003 patients, revealing that 77% were receiving opiate maintenance treatment, predominantly with methadone and buprenorphine, and highlighting significant patterns of drug use, including a notable percentage of injected medications.
  • The study also identified emerging abuse behaviors among certain analgesic opioids and showcased geographic variations in drug usage, demonstrating the efficacy of OPPIDUM in collecting valuable data relevant for addressing drug abuse at multiple levels

Article Abstract

It is important to assess drug abuse liability in 'real life' using different surveillance systems. OPPIDUM ('Observation of illegal drugs and misuse of psychotropic medications') surveillance system anonymously collects information on drug abuse and dependence observed in patients recruited in specialized care centers dedicated to drug dependence. The aim of this article is to demonstrate the utility of OPPIDUM system using 2015 data. OPPIDUM is a cross-sectional survey repeated each year since 1995. In 2015, 5003 patients described the modality of use of 10,159 psychoactive drugs. Among them, 77% received an opiate maintenance treatment: 68% methadone (half of them consumed capsule form) and 27% buprenorphine (39% consumed generic form). Brand-name buprenorphine is more often injected than generic buprenorphine (10% vs. 2%) and among methadone consumers 7% of methadone capsule consumers have illegally obtained methadone (vs. 9% for syrup form). The proportion of medications among psychoactive drugs injected is important (42%), with morphine representing 21% of the total psychoactive drugs injected and buprenorphine, 16%. OPPIDUM highlighted emergent behaviors of abuse with some analgesic opioids (like tramadol, oxycodone or fentanyl), pregabalin, or quetiapine. OPPIDUM highlighted variations of drugs use regarding geographic approaches or by drug dependence care centers (like in harm reduction centers). OPPIDUM clearly demonstrated that collection of valid and useful data on drug abuse is possible, these data have an interest at regional, national and international levels.

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http://dx.doi.org/10.1016/j.therap.2017.01.010DOI Listing

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