AI Article Synopsis
- The HID-Ion AmpliSeq™ Identity Panel amplifies a total of 124 SNPs—90 autosomal and 34 Y-SNPs—using the Ion Torrent PGM™ platform for genetic analysis.
- The study focused on 105 Basques, finding all loci in Hardy-Weinberg equilibrium and no significant associations among them.
- Forensic results indicated a combined match probability of 5.74×10 and a 99.99998% power of exclusion, showcasing the panel's potential for effective paternity testing and human identification in forensic applications.
Article Abstract
The HID-Ion AmpliSeq™ Identity Panel amplifies 90 autosomal SNPs and 34 Y- SNPs with massively parallel sequencing (MPS) using the Ion Torrent PGM™ platform. In the present study, 105 Basques were analyzed to assess this panel. All loci were in Hardy-Weinberg equilibrium and no association between them was detected. Forensic parameters were calculated as 5.74×10 for combined match probability and 99.99998% for combined power of exclusion. In conclusion, the HID Identity panel and the use of this new MPS technology are very promising tools for paternity testing and human identification in routine casework in the forensic field.
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| http://dx.doi.org/10.1016/j.fsigen.2017.03.010 | DOI Listing |
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