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Variation of clearance considering viscosity of the solution used in the reservoir and following scleral lens wear over time. | LitMetric

Variation of clearance considering viscosity of the solution used in the reservoir and following scleral lens wear over time.

Cont Lens Anterior Eye

Professor- Université de Montréal, École d'optométrie, 3744 Jean-Brillant, Suite 190-70, Montréal H3T 1P1, Canada. Electronic address:

Published: August 2017

AI Article Synopsis

  • - This study investigates how a scleral lens settles on the eye and whether the fluid inside the lens affects this process.
  • - Researchers used an 18mm scleral lens with a specific clearance, comparing outcomes between two types of non-preserved solutions (gel vs. saline) over several hours.
  • - Results showed a mean settling of 70μm after 6 hours, with significant differences in nasal vs. temporal settling, but the type of fluid did not significantly impact the lens's settling behavior.

Article Abstract

Purpose: This study aims to evaluate the settling of a scleral lens and if this process is influenced by the nature of the fluid layer.

Methods: A prospective, non-randomized control study was performed using an 18mm scleral lens. They were fitted with a central clearance of 400 um at insertion. One eye was randomly assigned to be fitted with a non-preserved gel solution of carboxymethylcellulose, while the other was inserted with non-preserved saline. Measurements of clearance in 3 locations were taken (OCT) at baseline, every 30min up to 1h30 post insertion and every 2h thereafter up to 6h00 of wear. A two-way repeated measure analysis of variance (liquids×times) was used to test central, nasal and temporal fluid thickness.

Results: Following 6h of wear, the 18mm lens had a mean central settling of 70.0±9.8μm, 36.7±9.8μm of which occurred within the first 30min of wear. There was no significant difference between lenses filled with non-preserved saline to those with non-preserved gel. However, a paired comparison concluded to a significant difference between mean nasal settling (41.4μm) and temporal settling (20.4μm).

Conclusion: With respect to the lens studied, current results suggest that practitioners can evaluate the lens 30min post insertion and can estimate the amount of fluid that will remain after lens stabilization by doubling the value obtained initially. The use of non-preserved saline or non-preserved more viscous solution to fill the lens does not influence its settling.

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Source
http://dx.doi.org/10.1016/j.clae.2017.03.003DOI Listing

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