First report of OXA-232-producing Klebsiella pneumoniae strains in Tunisia.

Diagn Microbiol Infect Dis

EA7361, Université Paris-Sud, Université Paris-Saclay, LabEx Lermit, Bacteriology-Hygiene unit, APHP, Hôpital Bicêtre, Le Kremlin-Bicêtre, France; Associated French National Reference Center for Antibiotic Resistance: Carbapenemase-producing Enterobacteriaceae, Le Kremlin-Bicêtre, France; Evolution and Ecology of Resistance to Antibiotics Unit, Institut Pasteur-APHP-Université Paris Sud, Paris, France.

Published: June 2017

AI Article Synopsis

  • Eleven strains of carbapenem-resistant Klebsiella pneumoniae were collected from a military hospital in Tunis, Tunisia.
  • Three of these strains contained a specific carbapenemase gene that was recently discovered in France, indicating potential cross-border transmission.
  • The isolates were genetically similar and also produced an extended-spectrum β-lactamase named CTX-M-15, highlighting the presence of OXA-232 producers in North Africa.

Article Abstract

Eleven carbapenem-resistant Klebsiella pneumoniae isolates were recovered from the military hospital of Tunis, Tunisia. Three of these isolates carried the carbapenemase bla gene recently identified in France. These isolates were clonally related and co-expressed the extended-spectrum ß-lactamase, CTX-M-15. This work identified the occurrence of OXA-232 producers in North-African countries.

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Source
http://dx.doi.org/10.1016/j.diagmicrobio.2017.03.005DOI Listing

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