The saturated hydraulic conductivity ( ) is a key characteristic of porous media, describing the rate of water flow through saturated porous media. It is an indispensable parameter in a broad range of simulation models that quantify saturated and/or unsaturated water flow. The constant-head permeameter test is a common laboratory method to determine K on undisturbed soil samples collected from the field. In this paper we show that the application of this conventional method may result in a biased in the case of highly permeable media, such as the top layer of peat and gravel. Tubes in the conventional permeameter, that collect water under the sample, introduce a hydraulic head-dependent resistance for highly permeable media and result in an underestimation of . We present a simple and low-budget alternative of the constant-head permeameter test that overcomes the disadvantages of conventional permeameters. The new method was successfully tested on intact highly permeable peatmoss collected from a northern peatland. •Conventional constant-head permeameters underestimate of highly permeable media due to flow resistance in tubing systems•We developed the low-resistance permeameter to overcome this disadvantage.•Testing of the low-resistance permeameter demonstrated no systematic bias and successful application for highly permeable media.
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http://dx.doi.org/10.1016/j.mex.2017.02.002 | DOI Listing |
Int J Biol Macromol
January 2025
Centre for Advanced Composite Materials, Universiti Teknologi Malaysia (UTM), Johor Bahru 81310, Malaysia.
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View Article and Find Full Text PDFCryobiology
January 2025
Department of Mechanical Engineering, University of Minnesota, Minneapolis, MN, United States of America. Electronic address:
Osmotic stresses during cryoprotectant loading induce changes in cellular volume, leading to membrane damage or even cell death. Appropriate model-guided mitigation of these osmotic gradients during cryoprotectant loading is currently lacking, but would be highly beneficial in reducing viability loss during the loading process. To address this need, we reformulate the two-parameter formalism described by Jacobs and Stewart for cryoprotectant loading under the constraint of constant cell volume.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
School of Environmental Studies, China University of Geosciences, Wuhan 430074, China; State Environmental Protection Key Laboratory of Source Apportionment and Control of Aquatic Pollution, China University of Geosciences, Wuhan 430074, China.
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View Article and Find Full Text PDFActa Physiol (Oxf)
February 2025
Research Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, China.
The blood-brain barrier (BBB) is a highly selective, semipermeable barrier critical for maintaining brain homeostasis. The BBB regulates the transport of essential nutrients, hormones, and signaling molecules between the bloodstream and the central nervous system (CNS), while simultaneously protecting the brain from potentially harmful substances and pathogens. This selective permeability ensures that the brain is nourished and shielded from toxins.
View Article and Find Full Text PDFAAPS PharmSciTech
January 2025
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Paeoniflorin is a natural pharmaceutical ingredient with a widely biological activity. However, as a hydrophilic drug, the problem of low transdermal rate limits its clinical application. To overcome this shortage, LUVs were used as biocompatible carriers of paeoniflorin in this study.
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