Fruit Juice and Change in BMI: A Meta-analysis.

Context: Whether 100% fruit juice consumption causes weight gain in children remains controversial.

Objective: To determine the association between 100% fruit juice consumption and change in BMI or BMI score in children.

Data Sources: PubMed, Embase, CINAHL, and Cochrane databases.

Study Selection: Longitudinal studies examining the association of 100% fruit juice and change in BMI measures were included.

Data Extraction: Two independent reviewers extracted data using a predesigned data collection form.

Results: Of the 4657 articles screened, 8 prospective cohort studies ( = 34 470 individual children) met the inclusion criteria. Controlling for total energy intake, 1 daily 6- to 8-oz serving increment of 100% fruit juice was associated with a 0.003 (95% CI: 0.001 to 0.004) unit increase in BMI score over 1 year in children of all ages (0% increase in BMI percentile). In children ages 1 to 6 years, 1 serving increment was associated with a 0.087 (95% confidence interval: 0.008 to 0.167) unit increase in BMI score (4% increase in BMI percentile). 100% fruit juice consumption was not associated with BMI score increase in children ages 7 to 18 years.

Limitations: All observational studies; studies differed in exposure assessment and covariate adjustment.

Conclusions: Consumption of 100% fruit juice is associated with a small amount of weight gain in children ages 1 to 6 years that is not clinically significant, and is not associated with weight gain in children ages 7 to 18 years. More studies are needed in children ages 1 to 6 years.