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Analysis of quantitative OCT and SS-OCTA metrics three months after initiation of intravitreal faricimab for treatment-recalcitrant neovascular AMD.
Eye (Lond)
January 2025
Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Purpose: To utilize optical coherence tomography (OCT) and SS-OCT angiography (SS-OCTA) for quantifying morphological changes seen in eyes with recalcitrant neovascular age-related macular degeneration (nAMD) transitioned to intravitreal faricimab injections during the manufacturer's recommended induction phase of treatment.
Methods: Fifty-four treatment-recalcitrant patients (60 eyes) were recruited. OCT and SS-OCTA images were obtained at 0 and 3 months.
Assessment of corneal vessels activity through the 'Barcode sign' of corneal OCT.
Eye (Lond)
January 2025
Division of Clinical Neuroscience, Department of Ophthalmology, University of Nottingham, Nottingham, UK.
Background/objectives: Anterior segment optical Coherence Tomography (AS-OCT) is used extensively in imaging the cornea in health and disease. Our objective was to analyse and monitor corneal vascularisation (CVas) through the corresponding back-shadows visible on AS-OCT.
Subjects/methods: AS-OCT scans were obtained from 26 consecutive patients (eyes) with CVas of different aetiologies.
Poor fixation stability does not account for motion perception deficits in amblyopia.
Sci Rep
January 2025
Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, Canada.
People with amblyopia show deficits in global motion perception, especially at slow speeds. These observers are also known to have unstable fixation when viewing stationary fixation targets, relative to healthy controls. It is possible that poor fixation stability during motion viewing interferes with the fidelity of the input to motion-sensitive neurons in visual cortex.
View Article and Find Full Text PDFAnalysis of the effect of congenital unilateral trochlear nerve paresis on retinal vascular density: a retrospective study.
J AAPOS
January 2025
University of Health Sciences, Department of Ophthalmology, Başakşehir Cam and Sakura City Hospital, Istanbul, Turkey.
Purpose: To use swept-source optical coherence tomography angiography (SS-OCTA) to investigate the alterations in retinal vascular density (VD) in patients presenting with congenital unilateral trochlear nerve palsy.
Methods: The medical records of patients diagnosed with congenital unilateral trochlear nerve palsy and those of a healthy control group were reviewed retrospectively. Comprehensive ocular examinations and SS-OCTA imaging were conducted.
Comparison of Vessel Responses Following Combined Sirolimus-Eluting and Endothelial Progenitor Cell Stent and Ultra-Thin Sirolimus-Eluting Stent Implantation by Serial Optical Coherence Tomography and Coronary Angioscopy: A Multicenter Observational Study.
Am J Cardiol
January 2025
Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
A dual-therapy sirolimus-eluting and CD34+ antibody-coated Combo Stent (DTS) has been developed to enhance endothelization and capture endothelial progenitor cells; however, vessel responses following DTS implantation remain unclear. Therefore, we evaluated early- and mid-term intravascular characteristics of DTS using intravascular imaging modalities. This multicenter, prospective, observational study enrolled 88 patients (95 lesions) who underwent DTS (43 patients, 48 lesions) or sirolimus-eluting Orsiro stent (SES, 45 patients, 47 lesions) implantation.
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