In pre-clinical Huntington's disease, normal behaviour is maintained despite neurodegeneration, suggesting a mechanism of compensation. Gregory, Long . present two mathematical models of compensation over time and their operationalisation for neuroimaging.
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http://dx.doi.org/10.1093/brain/awx022 | DOI Listing |
Rev Sci Instrum
January 2025
Applied and Adaptive Optics Laboratory, Department of Physics, Indian Institute of Space Science and Technology, Thiruvananthapuram 695547, Kerala, India.
In the present work, we propose an experimental setup to investigate the effect of atmospheric turbulence on user-defined beams. The user-defined beams were formed by writing reconfigurable patterns on a spatial light modulator, allowing the impact of atmospheric turbulence to be investigated simultaneously and in real time. The programmable controllability provides several flexibilities to the system, such as the ability to create different beam types simultaneously, control the separation between different beams, compensate for aberrations, and easily switch between different beam types.
View Article and Find Full Text PDFJ Cogn
January 2025
Department of Experimental Psychology, Ghent University, Belgium.
Many theories on cognitive effort start from the assumption that cognitive effort can be expended at will, and flexibly up- or down-regulated depending on expected task demand and rewards. However, while effort regulation has been investigated across a wide range of incentive conditions, few investigated the cost of effort regulation itself. Across four experiments, we studied the effects of reward expectancy and task difficulty on effort expenditure in a perceptual decision-making task (random-dot-motion) and a cognitive control task (colour-naming Stroop), and within each task comparted cues between short (cueing the next trial) and long (cueing the next six trials) prediction horizons.
View Article and Find Full Text PDFJ Neurol Sci
January 2025
Brigham MS Center, Brigham and Women's Hospital, Boston, MA, United States of America; Department of Neurology, Harvard Medical School, Boston, MA, United States of America. Electronic address:
Background: Cognitive impairment occurs frequently in persons with multiple sclerosis (PwMS) at some point in the course of the disease. However, not all PwMS develop cognitive difficulties suggesting a role for important moderating factors. We examined baseline predictors of cross-sectional and longitudinal change in cognitive performance in PwMS.
View Article and Find Full Text PDFJ Clin Med
January 2025
Division of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Texas, Southwestern Medical Center, Dallas, TX 75390, USA.
The risk of neonatal SARS-CoV-2 infection from the mother's own milk (MoM) in neonates who are exposed to maternal SARS-CoV-2 during the perinatal period remains unclear. We conducted a systematic review to assess the association between MoM feeding and neonatal SARS-CoV-2 infection in neonates who were born to SARS-CoV-2-positive pregnant persons. PubMed Central and Google Scholar were searched for studies published by 14 March 2024 that reported neonatal SARS-CoV-2 infection by feeding type.
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