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Peroperative administration of tranexamic acid in Roux-en-Y and one-anastomosis gastric bypass to reduce haemorrhage in patients with morbid obesity: protocol for randomised controlled trial (PATRY trial).
BMJ Open
May 2024
Department of Surgery, Franciscus Gasthuis en Vlietland, Rotterdam, Zuid-Holland, The Netherlands.
Article Synopsis
- The study investigates the effectiveness of tranexamic acid (TXA) in reducing postoperative bleeding in patients undergoing gastric bypass surgery, particularly in the context of Enhanced Recovery After Bariatric Surgery protocols.
- This multicenter, double-blind, randomized controlled trial will involve 1,524 participants across six bariatric centers in the Netherlands, comparing the effects of TXA against a placebo.
- Primary and secondary outcomes will assess hemorrhage rates, surgical details, complications, and costs, with the trial being ethically approved and results planned for publication.
Iatrogenic ureteral injury during colorectal surgery has a significant impact on patient outcomes: a French multicentric retrospective cohort study.
Colorectal Dis
July 2023
Department of Digestive Surgery, Assistance Publique Hôpitaux de Marseille, Timone Hospital, Aix Marseille University, Marseille, France.
Article Synopsis
- The study looked at how often ureteral injuries happen during colorectal surgery and what problems they can cause later on.* -
- Researchers found that among 202 patients, 55% had their injuries discovered after surgery, which can lead to more problems like longer hospital stays.* -
- If these injuries are spotted early, patients generally have fewer issues, but around 36% still end up with ongoing problems, and it can delay important cancer treatments.*
Flow Cytometry Based Platelet Reactivity Testing to Predict the Occurrence of Per-operative Solid Microemboli During Carotid Endarterectomy.
Eur J Vasc Endovasc Surg
June 2022
Department of Vascular Surgery, University Medical Centre Utrecht, Utrecht, The Netherlands. Electronic address:
Objective: Peri-operative antiplatelet therapy (APT) aims to prevent thrombotic events such as stroke. High platelet reactivity ,despite the use use of APT, increases the risk of thrombotic events. Transcranial Doppler imaging (TCD) is used to detect peri-operative microembolic signals (MES) during carotid endarterectomy (CEA).
View Article and Find Full Text PDFElectrical muscle stimulation in thomboprophylaxis: review and a derived hypothesis about thrombogenesis-the 4th factor.
Springerplus
July 2016
ICU, Limassol General Hospital, Eptanisou 2, Agios Nicolaos, 3100 Limassol, Cyprus.
Introduction: Electrical muscle stimulation (EMS) is an FDA-approved thromboprophylactic method. Thrombus pathogenesis is considered to depend on factors related to components of the vessel wall, the velocity of blood, and blood consistency-collectively known as, the Virchow's triad.
Objective: The testimony supporting the thromboprophylactic effects of the EMS is reviewed.
Endovascular treatment of ruptured intracranial aneurysms: Indications, techniques and results.
Diagn Interv Imaging
May 2016
Department of diagnostic and therapeutic neuroradiology, Neurology Hospital, Central Hospital, 29, avenue du Maréchal-de-Lattre-de-Tassigny, CO 60034, 54035 Nancy cedex, France.
Rupture of an intracranial aneurysm is a diagnostic and therapeutic emergency. Occlusion of the aneurysm with coils is the first line treatment and should be performed promptly to avoid any further rupture, which carries a poor prognosis. Most aneurysms are accessible to this type of treatment.
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