The voice is an important part of human identity. The voice is susceptible to impact of hormons mainly sexual hormons. The larynx is one of secondary sex characacteristics. Disorders of voice pose serious obstacle to full social integration in male to female and female to male transsexuals. The causes of transsexuality are still a matter of considerable debate. Now it is considered that, big nucleus suprachiasmaticus in the hypothalamus may be a cause of transsexuality. The aim of phonosurgery in transsexual patients is to gain acceptable voice by the patients. Proper preoperative assessment by the use of HRCT 3D imaging of the larynx and phoniatric counseling yields realistic postoperative results and verify patients expectations.
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Allergy Asthma Proc
January 2025
2nd Respiratory Department, Attikon University Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece.
Remission of asthma can occur as part of the natural history of the disease; however, the use of biologics can result in disease remission in some patients. In this post hoc analysis of the RELIght study, we aimed to evaluate clinical remission in real life among patients treated with mepolizumab, to detect possible differences between "remitters" and "nonremitters," and to evaluate possible predictors of remission. Clinical remission was defined as the absence of asthma exacerbations, discontinuation of oral corticosteroids (OCS), achievement of asthma control (Asthma Control Test [ACT] ≥ 20), and stable or improved lung function.
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Department of Primary and Community Care, Radboud University Medical Centre, Radboud Institute for Health Sciences, Geert Grooteplein 10, Nijmegen, 6500HB, the Netherlands.
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Division of General Internal Medicine, Colorado Clinical & Translational Sciences Institute, and the Adult & Child Center for Outcomes Research & Delivery Science, University of Colorado School of Medicine, 1890 N. Revere Ct., Aurora, CO, 80045, USA.
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View Article and Find Full Text PDFJ Neuroeng Rehabil
December 2024
School of Information Science and Technology, Fudan University, Shanghai, 200433, China.
For surface electromyography (sEMG) based human-machine interaction systems, accurately recognizing the users' gesture intent is crucial. However, due to the existence of subject-specific components in sEMG signals, subject-specific models may deteriorate when applied to new users. In this study, we hypothesize that in addition to subject-specific components, sEMG signals also contain pattern-specific components, which is independent of individuals and solely related to gesture patterns.
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