The number of patients diagnosed with pulmonary nodules increased as more patients with high risk of lung cancer choose low-dose computed tomography (CT) scans for the screening of cancer. Clinicians might get two questions from the patients: what is the definite diagnosis of the nodule? What should we do? We have already got many guidelines trying to solve these problems. There are also several prediction models for pulmonary nodules. However, guidelines are not suitable for all types of patients, and the reality of patients is more complicated. Here we reported a 58-year-old man with a lung nodule in the right upper lobe, which was occasionally found during a period of pneumonia. We suggested two periods of follow-up, and the patient was also admitted to a clinical trial about circulating tumor cells (CTCs). He finally accepted surgical excision with a pathologic diagnosis of adenocarcinoma. This case suggests that: we might suggest CT surveillance for patients with solid nodules about 8 mm maximum diameter; three-dimensional reconstruction of CT scans could provide more information about the details of nodules; CTCs counts of peripheral blood could be considered as a potential clue for malignancy.
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http://dx.doi.org/10.21037/tlcr.2017.02.01 | DOI Listing |
Diagnostics (Basel)
December 2024
Department of Internal Medicine, Division of Rheumatology, Mayo Clinic, Jacksonville, FL 32224, USA.
Pulmonary involvement is commonly observed in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), presenting with manifestations such as diffuse alveolar hemorrhage, inflammatory infiltrates, pulmonary nodules, and tracheobronchial disease. We aimed to identify distinct subgroups of tracheobronchial disease patterns in patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) using latent class analysis (LCA), and to evaluate their clinical characteristics and outcomes. We conducted a retrospective cohort study using electronic medical records of patients aged >18 years diagnosed with AAV and tracheobronchial disease between 1 January 2002 and 6 September 2022.
View Article and Find Full Text PDFDiagnostics (Basel)
December 2024
College of Computer Science and Engineering, Taibah University, Medina 41477, Saudi Arabia.
Computer-aided diagnostic systems have achieved remarkable success in the medical field, particularly in diagnosing malignant tumors, and have done so at a rapid pace. However, the generalizability of the results remains a challenge for researchers and decreases the credibility of these models, which represents a point of criticism by physicians and specialists, especially given the sensitivity of the field. This study proposes a novel model based on deep learning to enhance lung cancer diagnosis quality, understandability, and generalizability.
View Article and Find Full Text PDFJ Cardiothorac Surg
January 2025
Department of Oncology, The 969th Hospital of the PLA joint Logistics Support Force, No. 57, Aimin Street, Xincheng District, Hohhot City, Inner Mongolia Autonomous Region, 010051, China.
Background: The accuracy and reliability of identified biomarkers in differentiating early non-small cell lung cancer (NSCLC) remain suboptimal, thereby impeding the timely detection of NSCLC.The objective of this research is to examine the expression level and diagnostic utility of miR-668-3p in individuals with NSCLC, along with its effectiveness and predictive capacity in the combined diagnosis of early-stage NSCLC using serum markers.
Methods: The research included 117 NSCLC patients and 101 pulmonary nodule patients (controls).
BMC Med Imaging
January 2025
School of Medical Technology, Shaanxi University of Chinese Medicine, Xian Yang, 712046, China.
Objective: This study aims to evaluate the efficacy of two free-breathing magnetic resonance imaging (MRI) sequences-spiral ultrashort echo time (spiral UTE) and radial volumetric interpolated breath-hold examination (radial VIBE).
Methods: Patients were prospectively enrolled between February 2021 and September 2022. All participants underwent both 3T MRI scanning, utilizing the radial VIBE sequence and spiral UTE sequence, as well as standard chest CT imaging.
Chest
January 2025
National Center for Respiratory Medicine; State Key Laboratory of Respiratory Health and Multimorbidity; National Clinical Research Center for Respiratory Diseases; Institute of Respiratory Medicine, Chinese Academy of Medical Sciences; Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China. Electronic address:
A 34-year-old man who did not use tobacco complained of hemoptysis with a small volume, severe dry cough, and low-grade fever for 5 months. He denied dyspnea, chest pain, night sweats, or weight loss. Chest CT scanning showed nodules with a cavity in the lower left lung.
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