The Tameside Hospital Admiral Nursing Service, which I am part of, was introduced as a direct result of a complaint raised by the carer of a patient living with dementia.
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[Effect of moxibustion on learning-memory ability in rats with vascular dementia based on hippocampal Mst1/NF-κB p65 pathway].
Zhongguo Zhen Jiu
January 2025
Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Provincial Hospital of TCM, Nanjing 210029, China; Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu Province.
Objective: To observe the effects of (transforming stasis and unblocking collaterals) moxibustion on learning-memory ability and hippocampal mammalian sterile 20-like kinase 1 (Mst1)/nuclear factor κB (NF-κB) p65 pathway related to inflammatory response in rats with vascular dementia (VD).
Methods: A total of 60 male Wistar rats of SPF grade were randomly divided into a sham operation group (12 rats) and a modeling group (48 rats). VD model was established by the method of modified bilateral common carotid artery permanent ligation in the modeling group.
Bring dying at home: What facilitates and hinders home-based end-of-life care for people living with dementia?-A systematic review and meta-ethnography protocol.
PLoS One
January 2025
Nursing Studies, School of Health in Social Science, University of Edinburgh, Edinburgh, United Kingdom.
Background: Although home-based end-of-life care is more in line with the preferences of people living with dementia, operationalizing this ideal remains challenging. Many people living with dementia are still unable to die at home or receive end-of-life care at home. This review aims to apply meta-ethnography to synthesize existing qualitative studies, to identify the facilitators and barriers of home-based end-of-life care for people living with dementia.
View Article and Find Full Text PDFTransforming dementia research into practice: a multiple case study of academic research utilization strategies in Dutch Alzheimer Centres.
Health Res Policy Syst
January 2025
Erasmus School of Health Policy & Management, PO Box 1738, 3000 DR, Rotterdam, Netherlands.
Background: Non-pharmacological dementia research products, such as social and behavioural interventions, are generated in traditional university settings. These often experience challenges to impact practices that they were developed for. The Netherlands established five specialized academic health science centres, referred to as Alzheimer Centres, to structurally coordinate and facilitate the utilization of dementia research knowledge.
View Article and Find Full Text PDFPractical guidelines for developing digital health solutions to increase equity in dementia care in the UK.
Front Digit Health
December 2024
London School of Hygiene and Tropical Medicine Uganda Research Unit, Medical Research Council (Uganda), Entebbe, Uganda.
Background: Digital Healthcare Solutions (DHS) are transforming healthcare by improving patients' experiences, safety and quality of care. However, despite all the proposed and observed advantages of DHS, a growing body of research suggests that these DHS are not equally accessible to all. This research aimed to assess whether equity frameworks for digital health solutions can be used to guide the development of digital health solutions to increase access to care for dementia patients in the UK and, thereafter, develop practical guidelines to guide the design of equitable DHS products to address this growing issue.
View Article and Find Full Text PDFNext generation brain health: transforming global research and public health to promote prevention of dementia and reduce its risk in young adult populations.
Lancet Healthy Longev
December 2024
Global Brain Health Institute (GBHI), Trinity College Dublin, Dublin, Ireland; Centre for Dementia Research, School of Health, Leeds Beckett University, Leeds, UK.
Efforts to prevent dementia can benefit from precision interventions delivered to the right population at the right time; that is, when the potential to reduce risk is the highest. Young adults (aged 18-39 years) are a neglected population in dementia research and policy making despite being highly exposed to several known modifiable risk factors. The risk and protective factors that have the biggest effect on dementia outcomes in young adulthood, and how these associations differ across regions and groups, still remain unclear.
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