This article describes a novel method for the preparation of a biodegradable non-woven poly(ε-caprolactone) fabric with a partially embedded apatite surface designed for application as a scaffold material for bone tissue engineering. The non-woven poly(ε-caprolactone) fabric was generated by the electro-spinning technique and then apatite was coated in simulated body fluid after coating the PVA solution containing CaCl ·2H O. The apatite crystals were partially embedded or fully embedded into the thermoplastic poly(ε-caprolactone) fibers by controlling the degree of poly(ε-caprolactone) fiber surface melting in a convection oven. Identical apatite-coated poly(ε-caprolactone) fabric that did not undergo heat-treatment was used as a control. The features of the embedded apatite crystals were evaluated by FE-SEM, AFM, EDS, and XRD. The adhesion strengths of the coated apatite layers and the tensile strengths of the apatite coated fabrics with and without heat-treatment were assessed by the tape-test and a universal testing machine, respectively. The degree of water absorbance was assessed by adding a DMEM droplet onto the fabrics. Moreover, cell penetrability was assessed by seeding preosteoblastic MC3T3-E1 cells onto the fabrics and observing the degrees of cell penetration after 1 and 4 weeks by staining nuclei with DAPI. The non-woven poly(ε-caprolactone) fabric with a partially embedded apatite surface showed good water absorbance, cell penetrability, higher apatite adhesion strength, and higher tensile strength compared with the control fabric. These results show that the non-woven poly(ε-caprolactone) fabric with a partially embedded apatite surface is a potential candidate scaffold for bone tissue engineering due to its strong apatite adhesion strength and excellent cell penetrability. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 1973-1983, 2017.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/jbm.a.36069 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Multifunctional electrospun nanofiber films of polyacrylonitrile and polyvinyl alcohol incorporating rhamnose and therapeutic agents for enhanced healing of infected burn wounds.
J Biomater Sci Polym Ed
January 2025
Department of Microbiology, University of Central Punjab, Lahore, Pakistan.
Infected burn wounds present significant clinical challenges due to delayed healing and risk of infection, necessitating advanced treatments that offer both antimicrobial and regenerative properties. This study aimed to develop and evaluate multifunctional electrospun nanofiber films incorporating rhamnose (as an angiogenic agent) and therapeutic agents, namely fluticasone, mupirocin, ciprofloxacin, and silver sulfadiazine, for the enhanced healing of infected burn wounds. Nanofibers containing rhamnose, polyacrylonitrile, polyvinyl alcohol and therapeutic agents were fabricated electrospinning.
View Article and Find Full Text PDFStrategy for Fabricating Multiple-Shape Memory Polymeric Materials Based on Solid State Mixing.
ACS Macro Lett
January 2025
The Bio-Med-Chem Doctoral School of the University of Lodz and Lodz Institutes of the Polish Academy of Sciences, Banacha 12/16, Lodz 90-237, Poland.
Article Synopsis
- Researchers propose a new method for creating multiple shape memory polymers (SMPs) by mixing immiscible polymers under high pressure and shear, rather than traditional blending techniques.
- This approach allows for nanoscale homogeneity (40-95 nm) in the blends, improving both shape memory and mechanical performance.
- The study focused on a blend of polypropylene (PP) and polystyrene (PS), demonstrating that the processed blend achieves a strong triple shape memory effect with high shape fixation and recoverability, along with adjustable transition temperatures.
Fit accuracy and fracture resistance evaluation of advanced lithium disilicate crowns (in- vitro study).
BMC Oral Health
January 2025
Division of Fixed Prosthodontics, Conservative Dentistry Department, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.
Background: Increasing demand for durable and aesthetically pleasing dental restorations, including laminates, inlays, onlays, and crowns, has led to advancements in all-ceramic systems, particularly with the development of advanced lithium disilicate materials. However, limited data on the fit accuracy and fracture resistance of these materials restricts their wider application in clinical restorative practices.
Aim Of The Study: This in vitro study aims to compare the marginal and internal fit, assess the fracture resistance, and evaluate the failure modes of crowns fabricated from advanced and conventional lithium disilicate materials.
Study on the preparation and design of chenille/polyester integrated yarns and its acoustic properties.
Sci Rep
January 2025
Shanghai Frontiers Science Research Center of Advanced Textiles, College of Textiles, Donghua University, Shanghai, 201620, China.
With the rapid development of industrialization and urbanization, the impact of noise on people's health has become an increasingly serious issue, but it is still a challenge for the reducing the noise due to its complex property. Textiles with many loose porous structures have gained much significant attentions, thus chenille yarns with plush fibers on the surface, and polyester monofilament were chosen to fabricate the integrated knitting yarns, and their fundamental and mechanical properties were fully evaluated. The results showed that the diameter and braiding angle of the blended yarns decreased with the increase of pitch, resulting in a linear correlation of R > 0.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!