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Antiviral Drug-Resistant Influenza B Viruses Carrying H134N Substitution in Neuraminidase, Laos, February 2016. | LitMetric

AI Article Synopsis

Article Abstract

In February 2016, three influenza B/Victoria/2/87 lineage viruses exhibiting 4- to 158-fold reduced inhibition by neuraminidase inhibitors were detected in Laos. These viruses had an H134N substitution in the neuraminidase and replicated efficiently in vitro and in ferrets. Current antiviral drugs may be ineffective in controlling infections caused by viruses harboring this mutation.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367415PMC
http://dx.doi.org/10.3201/eid2304.161876DOI Listing

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