Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jns.2017.02.005 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Obstacle Course Races Present a Risk of Musculoskeletal, Knee, and Anterior Cruciate Ligament Injury, Especially in High-Impact Landing Maneuvers and Female Athletes: A Systematic Review.
Arthrosc Sports Med Rehabil
December 2024
Department of Orthopedic Surgery & Rehabilitation, Loyola University Medical Center, Maywood, Illinois, U.S.A.
Purpose: To determine the incidence rate (IR) of anterior cruciate ligament (ACL) and associated musculoskeletal injuries in recreational and/or military-training obstacle course races (OCRs) and to determine whether there are any risk factors or features of OCRs impacting the rate of ACL injury in race participants.
Methods: This systematic review was performed in accordance with Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. Studies were identified using the following electronic databases: PubMed, EMBASE, Cochrane, and Scopus.
A pilot trial for efficacy confirmation of 6'-sialyllactose supplementation in GNE myopathy: Randomized, placebo-controlled trial.
Mol Genet Metab
January 2025
Department of Neurology, Pusan National University School of Medicine, Busan, Republic of Korea; Department of Neurology and Biomedical Research institute, Pusan National University Yangsan Hospital, Gyeongsangnam-do, Republic of Korea. Electronic address:
Article Synopsis
- GNE myopathy is a rare genetic muscle disorder that leads to weakness in the ankles and muscle degeneration, caused by mutations in the GNE gene that reduce sialic acid production.
- A clinical trial tested a supplement, 6'-sialyllactose (6SL), at doses of 3g and 6g to see if it could improve muscle strength and health, revealing better outcomes in muscle strength and reduced degeneration with the higher dose.
- The latest study involved 11 participants to compare 6SL with a placebo group over 48 weeks, finding no major differences in muscle strength but a significant degeneration in muscle fat measured by MRI, indicating muscle health issues, particularly in the placebo group.
No Evidence of Early Developmental Delay in Juvenile-Onset Huntington's Disease Patients.
Mov Disord Clin Pract
December 2024
Department of Psychiatry, Carver College of Medicine at the University of Iowa, Iowa City, Iowa, USA.
Background: Previous studies suggest that early developmental delay is a common feature of Juvenile-Onset Huntington's disease (JOHD), with highest incidence in those with very high CAG repeats (> 80). However, all reports of developmental delay in JOHD are exclusively based on retrospective review of medical charts. Comprehensive assessment of birth history metrics may provide better insight into the question of early life development in JOHD.
View Article and Find Full Text PDFIncidence, treatment patterns, and mortality for patients with breast cancer during the first year of the COVID-19 pandemic: a population-based study.
Breast Cancer Res Treat
December 2024
Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, USA.
Purpose: The COVID-19 pandemic created significant disruptions in the diagnosis and treatment of breast cancer (BC). Several public health measures were taken with limited evidence on their potential impact. In this observational study, we sought to compare the incidence of BC, treatment patterns, and mortality during 2020 versus 2018 and 2019.
View Article and Find Full Text PDFMaternal health and obstetric complications of genetic neuromuscular disorders in pregnancy: A systematic review.
Eur J Obstet Gynecol Reprod Biol
January 2025
Andhra Medical College, Vishakapatnam, Andhra Pradesh, India.
Article Synopsis
- Genetic neuromuscular disorders significantly impact muscle function and present challenges during pregnancy, necessitating a review of related obstetric outcomes.
- A systematic analysis of 28 studies revealed common complications such as polyhydramnios, preterm labor, and increased rates of cesarean sections among pregnant women with disorders like myotonic dystrophy and spinal muscular atrophy.
- Effective management of these high-risk pregnancies requires collaboration between neurologists and obstetricians, alongside further research to establish standardized care protocols.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!