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Notification of blood donors who test positive for transfusion-transmissible infections.
Vox Sang
January 2025
Donation and Policy Studies, Canadian Blood Services, Ottawa, Ontario, Canada.
Background And Objectives: Despite screening procedures, a few blood donors confirm positive for transfusion-transmissible infections and are deferred. Effective notification of laboratory results is essential to ensure that donors are advised of confirmed results and to seek medical care. Here we report results from post-notification interviews of Canadian Blood Services donors.
View Article and Find Full Text PDFEngaging with young professionals in transfusion medicine: Insights from a needs assessment survey targeting an international cohort.
Vox Sang
January 2025
Department of Public and Occupational Health, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.
Background And Objectives: Professionals who work or study in transfusion medicine under 40 years of age are considered young professionals (YPs) by the International Society of Blood Transfusion (ISBT). While the ISBT provides opportunities for YPs, their needs have to be assessed to customize initiatives in a way that could potentially improve their engagement. This survey aimed to assess the needs of YPs in transfusion medicine and understand their perspectives on future ISBT initiatives.
View Article and Find Full Text PDFInvestigating the impact of mitochondrial DNA: Insights into blood transfusion reactions and mitigation strategies.
Vox Sang
January 2025
Department of Laboratory Sciences, School of Paramedical and Rehabilitation Sciences, Mashhad University of Medical Sciences, Mashhad, Iran.
Background And Objectives: Although transfusion reactions occur in less than 2% of recipients, they are currently one of the most serious concerns in blood transfusion. Damage-associated molecular patterns (DAMPs) are released from injured, stressed or dead cells, leading to inflammation and immune system activation. One of the recognized DAMPs is mitochondrial DNA (mtDNA).
View Article and Find Full Text PDFAssessing reagents and techniques for identifying RhCE variants in routine serological testing.
Vox Sang
January 2025
Hemocentro Unicamp, Campinas, São Paulo, Brazil.
Background And Objectives: Identifying RhCE variants is essential to prevent alloimmunization and manage complex cases. Unfortunately, these variants are often only detected after antibody formation, as they may go unnoticed in serological tests. This study aimed to assess monoclonal antisera using various methodologies to define the reactivity patterns of some variants by variable expression of RhCE antigens.
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