The current study describes a simple, rapid and eco-friendly method for the synthesis of silver nanoparticles (AgNPs) using () leaf extract as stabilizer, bioreductant and capping agent. Synthesized AgNPs were characterized by UV-Visible spectroscopy (UV-Vis), X-ray diffraction (XRD), fourier transform infrared (FT-IR) spectroscopy, field emission scanning electron microscopy (FESEM) and energy dispersive X-ray spectroscopy (EDX). Generation of AgNPs was initially confirmed with the color change from yellow to dark brown which produces intense absorbance spectra at 440 nm in UV-Vis spectroscopy without any shifting of peaks. Further, XRD pattern confirms that the synthesized AgNPs was face centered cubic (fcc) crystalline in structure with an average size of 20 nm. On the other hand, FTIR spectrum reveals that the active metabolites like water soluble phenolic compounds, flavonoids, methylene groups, amides and carboxylate groups. These active biocompounds plays a vital role in the reduction of Ag into their nanoscale values, it also acts as a stabilizing and surface functionalization agent. FESEM micrographs of synthesized AgNPs shows spherical and hexagonal shaped well dispersed particles in the dimension ranging between 23 and 42 nm. EDAX confirms the presence of silver (Ag) as the major constituent element without any impurities; also substantiate the stability of generated AgNPs. The biomedical insights of nanoparticles (NPs) were assessed through radical scavenging and antibacterial properties. Additionally, synthesized AgNPs was also exhibits an excellent cytotoxic effect against human breast carcinoma cell lines (MCF-7). This study proves that synthesized AgNPs can be developed as a potential nano-drug formulation to combat pathogenic disease and also for the expansion of breast cancer therapy.
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http://dx.doi.org/10.1007/s12639-016-0773-6 | DOI Listing |
Odontology
January 2025
Oral Biology Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
Natural bone is a self-regenerating nanocomposite made of proteins and minerals. Such self-regenerative capacity can be negatively affected by certain diseases involving the bone or its surrounding tissues. Our study assesses the ability of bone grafting material to regenerate bone in animals who have artificially created critical-sized defects.
View Article and Find Full Text PDFNanomaterials (Basel)
January 2025
King Abdullah Institute for Nanotechnology, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
We aimed to synthesize silver nanoparticles (AgNPs) using (cardamom) extracts and assess the cytotoxicity and genotoxicity of the cardamom extract, -AgNPs, and the insecticide ATCBRA-commonly used for pest control-on the root system of (broad bean). The chemical composition of the aqueous cardamom extract was identified and quantified using GC-MS, revealing a variety of bioactive compounds also present in cardamom essential oil. These included α-terpinyl acetate (21.
View Article and Find Full Text PDFInt J Phytoremediation
January 2025
Water Management and Treatment Technologies Institute, King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia.
This study introduces a sustainable biological approach for synthesizing silver nanoparticles (AgNPs) using Conocarpus seeds, aimed at improving the adsorption and photocatalytic degradation of methylene blue (MB) in wastewater treatment. The photocatalytic efficiency of AgNPs, synthesized under varying concentrations of silver nitrate (AgNO) and pH levels, was evaluated, together with the effectiveness of a photocatalytic reactor. The synthesized samples were characterized using scanning electron microscopy (SEM), thermogravimetric analysis (TGA), Fourier-transform infrared (FT-IR) spectroscopy, and atomic force microscopy (AFM).
View Article and Find Full Text PDFACS Appl Bio Mater
January 2025
Department of Chemical Engineering, Indian Institute of Technology Tirupati, Tirupati, Andhra Pradesh 517619, India.
In the fast-paced quest for early cancer detection, noninvasive screening techniques have emerged as game-changers, offering simple and accessible avenues for precession diagnostics. In line with this, our study highlights the potential of silver nanoparticle-decorated titanium carbide MXene nanosheets (TiC_AgNPs) as an electroactive interface for the noninvasive diagnosis of oral carcinoma based on the prevalence of the salivary biomarker, tumor necrosis factor-α (TNF-α). An in situ reduction was utilized to synthesize the TiC_AgNPs nanohybrid, wherein TiC acts as the reducing agent, and the resulting nanohybrid was subjected to various characterization techniques to examine the optical, structural, and morphological attributes.
View Article and Find Full Text PDFCurr Pharm Biotechnol
January 2025
Assistant Professor, Dental Research Center, Department of Oral and Maxillofacial Pathology, School of Dentistry, Birjand University of Medical Sciences, Birjand, Iran.
Background: The increasing prevalence of antibiotic-resistant bacteria necessitates exploring nanotechnology as a potential solution for microbial elimination.
Objectives: This study aimed to investigate the antimicrobial and antioxidant effects of silver nanoparticles synthesized using aqueous extract from the Ephedra gerardiana (E. gerardiana) plant (EG@AgNPs).
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