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http://dx.doi.org/10.1136/bcr-2016-219127 | DOI Listing |
Ann Surg
August 2020
Department of Surgery, Stony Brook Medicine, Stony Brook, New York.
Background: A novel coronavirus (COVID-19) erupted in the latter part of 2019. The virus, SARS-CoV-2 can cause a range of symptoms ranging from mild through fulminant respiratory failure. Approximately 25% of hospitalized patients require admission to the intensive care unit, with the majority of those requiring mechanical ventilation.
View Article and Find Full Text PDFIntern Med
June 2020
Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Japan.
A 56-year-old healthy man who was a current smoker died from fulminant tracheobronchial aspergillosis despite a month of treatment with a combination of intravenous anti-fungal agents that had been started immediately after the diagnosis. This case report is important for understanding and managing fulminant Aspergillus infections in healthy subjects, although the pathogenesis and underlying pathways are still unknown.
View Article and Find Full Text PDFIntern Med
August 2018
Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Japan.
Invasive tracheobronchial aspergillosis (ITBA), a rare form of invasive pulmonary Aspergillus infection (IPA), is predominantly confined to the tracheobronchial tree. We herein report a case of ITBA with severe necrotic pseudomembrane in a 57-year-old woman with fulminant hepatitis and hemophagocytic syndrome. Bronchoscopic findings revealed a widespread pseudomembranous formation of the trachea and bronchi.
View Article and Find Full Text PDFBMJ Case Rep
March 2017
Rhode Island Hospital, Center for International Health Research, Providence, Rhode Island, USA.
Intern Med
March 2017
Department of Hematology, the Xinghai Hospital of Suzhou Industrial Park, China.
A 23-year-old man who had previously undergone allogeneic hematopoietic stem cell transplantation (allo-HSCT) for severe aplastic anemia was diagnosed with invasive laryngeal-tracheobronchial-pulmonary aspergillosis after presenting with a persistent dry cough at six months post-transplantation based on the findings of laryngoscopy and fiberoptic bronchoscopy. A fiberoptic bronchoscope was used to remove the obstructive material from the patient's airway and posaconazole plus caspofungin were administered to successfully to treat the patient. Our report suggests that laryngoscopy and fiberoptic bronchoscopy should be considered as alternative approaches to the diagnosis and treatment of allo-HSCT recipients with persistent respiratory symptoms when invasive laryngeal aspergillosis and invasive tracheobronchial aspergillosis are suspected.
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