Modelling work in the Marion Lake Project has led to a number of simulation models that trace the fate of primary production through consumer components of the lake ecosystem. Two of these models illustrate extremes in realism and generality: a simple compartment-flow system, and a detailed population model that represents density and individual growth of 24 major animal species. Both models are adequate to describe normal seasonal changes in the variables that they represent, but the simple model may give better predictions about response of the system to disturbance. Modelling efforts would have been much more successful if they had been initiated at the start of the project rather than after much field data had already been collected.
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J Neurosurg
December 2024
4Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah.
Objective: Cost-minimization approaches for the treatment of patients with chronic subdural hematoma (cSDH) are important given the increasing incidence of this pathology, particularly among elderly patients receiving antiplatelet and anticoagulation medications. The use of middle meningeal artery embolization (MMAE) as an adjunct to surgical evacuation has shown promise in reducing surgical recurrence; however, additional costs are involved with this procedure. Using their institutional experience, the authors identified thresholds for cost and the cSDH surgical recurrence rate that could influence treatment decisions in patients requiring surgical evacuation for cSDH.
View Article and Find Full Text PDFEcotoxicol Environ Saf
December 2024
Life Sciences, Hamburg University of Applied Science, Ulmenliet 20, Hamburg D-21033, Germany.
Cardiooncology
November 2024
Division of Cardiovascular Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, 676 N. St. Clair, Suite 600, Chicago, IL, 60611, USA.
Background: Global longitudinal strain (GLS) has been used to identify patients at risk for cancer-therapy related cardiac dysfunction (CTRCD). However, there is limited data on the effectiveness of initiating cardioprotective therapy based on a strain-guided strategy in early stage HER2+ breast cancer patients. This randomized clinical trial assessed if treatment with carvedilol based on a strain-guided strategy can prevent development of CTRCD in HER2+ breast cancer patients on non-anthracycline based regimens.
View Article and Find Full Text PDFHarmful Algae
September 2024
Wright State University - Lake Campus, Department of Biological Sciences, Agriculture and Water Quality Education Center, Celina, Ohio 45822, USA.
Dev Cogn Neurosci
August 2024
Department of Psychiatry, Oregon Health & Science University, Portland, OR, United States; Department of Psychiatry, University of Utah, Salt Lake City, UT, United States; Center for Mental Health Innovation, Oregon Health & Science University, Portland, OR, United States. Electronic address:
Background: Transparency can build trust in the scientific process, but scientific findings can be undermined by poor and obscure data use and reporting practices. The purpose of this work is to report how data from the Adolescent Brain Cognitive Development (ABCD) Study has been used to date, and to provide practical recommendations on how to improve the transparency and reproducibility of findings.
Methods: Articles published from 2017 to 2023 that used ABCD Study data were reviewed using more than 30 data extraction items to gather information on data use practices.
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