Neural differentiation of amphibian gastrula ectoderm exposed to phorbol ester.

Rouxs Arch Dev Biol

Institut für Molekularbiologie und Biochemie, Freie Universität Berlin, Arnimallee 22, D-1000, Berlin 33.

Published: February 1987

Ectoderm from early gastrula stages of amphibians was isolated and treated with phorbol 12-myristate 13-acetate. The ectoderm formed neural tissue and in a few cases also mesenchyme and melanophores. The control explants formed atypical epidermis. In explants treated with phorbol 12-myristate 13-acetate the mitotic rate was increased.

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http://dx.doi.org/10.1007/BF00402036DOI Listing

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