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Graded porous scaffold mediates internal fluidic environment for 3D in vitro mechanobiology.
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Department of Biomedical Engineering, Faculty of Science and Engineering, Swansea University, Swansea, United Kingdom; Zienkiewicz Institute for Modelling Data and AI, Swansea University, Swansea, United Kingdom. Electronic address:
Most cell types are mechanosensitive, their activities such as differentiation, proliferation and apoptosis, can be influenced by the mechanical environment through mechanical stimulation. In three dimensional (3D) mechanobiological in vitro studies, the porous structure of scaffold controls the local mechanical environment that applied to cells. Many previous studies have focused on the topological design of homogeneous scaffold struts.
View Article and Find Full Text PDFA case study: exploring the impact of 3D printed models on cognitive integration during clinical skills training.
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Department of Medical Education, University of Illinois College of Medicine, Illinois, USA.
Background: Cognitive integration occurs when trainees make conceptual connections between relevant knowledges and is known to improve learning. While several experimental studies have demonstrated how text and audio-visual instruction can be designed to enhance cognitive integration, clinical skills training in real-world contexts may require alternative educational strategies. Introducing three-dimensional (3D) printed models during clinical skills instruction may offer unique learning opportunities to support cognitive integration.
View Article and Find Full Text PDFImpacts of immersive 3D videos on students' surgical learning compared to 2D videos: a randomized controlled trial.
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Department of Gynecological and Breast Surgery and Oncology, Pitié-Salpêtrière, Assistance Publique des Hôpitaux de Paris (AP-HP), University Hospital, Paris, France.
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View Article and Find Full Text PDFCan Peer Acceptance and Perceptual Accuracy Impact the Effectiveness of Two Formats of a Preventative Intervention on Functional Subtypes of Aggression in Youth?
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Center for Youth Development & Intervention, The University of Alabama, Tuscaloosa, AL, 35487, USA.
Coping Power (CP) is an empirically supported school-based intervention for children at risk for aggression. A child's social status with peers and the extent to which they accurately perceive it are important aspects of preadolescent social development that may influence how intervention format affects disruptive behavior outcomes. Further, reactive (RA) and proactive (PA) functional subtypes of aggression have differential relations with peer acceptance.
View Article and Find Full Text PDFTowards constructing a generalized structural 3D breathing human lung model based on experimental volumes, pressures, and strains.
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Department of Mechanical Engineering, University of California Riverside, Riverside, California, United States of America.
Respiratory diseases represent a significant healthcare burden, as evidenced by the devastating impact of COVID-19. Biophysical models offer the possibility to anticipate system behavior and provide insights into physiological functions, advancements which are comparatively and notably nascent when it comes to pulmonary mechanics research. In this context, an Inverse Finite Element Analysis (IFEA) pipeline is developed to construct the first continuously ventilated three-dimensional structurally representative pulmonary model informed by both organ- and tissue-level breathing experiments from a cadaveric human lung.
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