Lucio's phenomenon is an uncommon reaction characterized by severe necrotizing cutaneous lesions that occurs in patients with Lucio's leprosy and lepromatous leprosy. It is considered by some authors as a variant of type 2 or 3 reaction. Death can occur because of blood dyscrasia or sepsis. Precipitating factors include infections, drugs and pregnancy. We report a 31-year-old female patient exhibiting both clinical and histopathological features of lepromatous leprosy and Lucio's phenomenon presenting favorable response to treatment. We complement our report with a literature review of the Brazilian cases of Lucio's phenomenon published in Portuguese and English.
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http://dx.doi.org/10.1590/abd1806-4841.20164370 | DOI Listing |
J Am Acad Dermatol
December 2024
Sri Aurobindo Medical College and Post-Graduate Institute, Indore (M.P.), India, 453555.
SAGE Open Med Case Rep
December 2024
Division of Dermatology, Department of Medicine, University of Alberta, Edmonton, AB, Canada.
Leprosy remains a persistent health challenge in endemic regions with cases rising in non-endemic regions such as North America. Patients with leprosy present with a variety of symptoms including limited skin lesions in tuberculoid leprosy to extensive lesions and high bacterial proliferation in lepromatous leprosy. This case report details a 77-year-old Canadian man of South Asian descent with lepromatous leprosy and Lucio's phenomenon in Western Canada.
View Article and Find Full Text PDFAm J Dermatopathol
January 2025
Service of Dermatology "Dr. Mario Magaña Lozano' of the Hospital General de México "Dr. Eduardo Liceaga', S.S. (Ministry of Health)/Faculty of Medicine, Universidad Nacional Autónoma de México (UNAM), Mexico City, México.
Mycobacterium leprae and M. lepromatosis, the causative agents of leprosy, have left a mark on human history. Despite advances in health care, leprosy continues to affect millions worldwide, often leading to complications, mostly neural, due to delayed diagnosis and treatment.
View Article and Find Full Text PDFJ Affect Disord
January 2025
Department of General Psychology, University of Padua, Via Venezia 8, 35131 Padua, Italy; Padova Neuroscience Center (PNC), University of Padua, Via Orus 2/B, 35131 Padua, Italy.
Background: Human body odors (BOs) serve as an effective means of social communication, with individuals exposed to emotional BOs experiencing a partial replication of the sender's affective state. This phenomenon may be particularly relevant in conditions where social interactions are impaired, such as social anxiety. Our study aimed to investigate if emotional human BOs could augment the benefits of mindfulness-based interventions.
View Article and Find Full Text PDFBMJ Case Rep
July 2024
Dermatology, Venereology and Leprosy, Madras Medical College, Chennai, Tamil Nadu, India.
Lucio leprosy is a diffuse non-nodular form of lepromatous leprosy. Lucio phenomenon is a type of reactional state which occurs in untreated cases due to the bacillary invasion of endothelial cells. We hereby describe a histopathologically confirmed case of Lucio leprosy with Lucio phenomenon.
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