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Postnatal Neural Stem Cells: Probing Their Competence for Cortical Repair. | LitMetric

Postnatal Neural Stem Cells: Probing Their Competence for Cortical Repair.

Neuroscientist

1 Univ Lyon, Université Claude Bernard Lyon 1, Inserm, Stem Cell and Brain Research Institute, Bron, France.

Published: December 2017

AI Article Synopsis

Article Abstract

There is growing evidence for a tentative cellular repair in the forebrain following perinatal injuries. In this review, we present the evidences and shortcomings in this regenerative attempt. We discuss recent progress in elucidating the origin, diversity, and competence of postnatal neural stem cells/progenitor cells. Finally, we propose new strategies to recruit postnatal progenitors to generate specific subtypes of cortical neurons or oligodendrocytes, thereby allowing the development of tailor-made approaches to treat perinatal brain injuries.

Download full-text PDF

Source
http://dx.doi.org/10.1177/1073858417697036DOI Listing

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