Purpose: To study the outcomes and impact of a mobile unit for retinopathy of prematurity (ROP) screening and management at urban Neonatal Intensive Care Units (NICUs).
Study Design: Public health intervention study.
Methods: This study was conducted in 2012. Staff of a mobile unit assessed all infants aged 32 weeks or less and/or weight 1250 g or less admitted in five NICUs between 2009 and 2011. An ophthalmologist performed bedside ROP screening through dilated pupils using indirect ophthalmoscopy. ROP was graded and managed as per the International Classification of ROP treatment guidelines. Counseling and laser treatment were the interventions. The incidence, grade, and determinants of ROP were estimated. Direct and indirect costs were calculated to estimate the unit cost of screening and managing a child with ROP using the mobile unit.
Result: The study sample included 104 preterm/underweight infants. The prevalence of ROP of different grades in either eye was 32.7% (95% confidence intervals: 23.7-41.7). ROP Stage I was present in 75% of these eyes. The mobile unit could help in preventing/reducing visual disability in 5 infants with advanced stages of ROP. The unit cost of ROP screening, identifying one child with ROP, and addressing visual disability due to ROP was US $310, 950, and 6500, respectively.
Conclusion: A mobile screening is likely feasible and cost-effective method to detect ROP and offer timely intervention in urban areas with limited resources.
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http://dx.doi.org/10.4103/0974-620X.200684 | DOI Listing |
Antimicrob Agents Chemother
January 2025
Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
A strain positive for the metallo-beta-lactamase gene and resistant to trimethoprim-sulfamethoxazole was unexpectedly isolated from a surveillance rectal swab. The characterization of the strain revealed carriage of a 91 kb integrative and conjugative element (ICE) harboring several resistance determinants [, , , , ∆, , and ], closely related with a group of -type ICEs widespread among and other pseudomonads. Results highlighted the possible spreading of similar elements to , mediating the acquisition of relevant resistances.
View Article and Find Full Text PDFJ Am Heart Assoc
January 2025
Department of Population Health Sciences Weill Cornell Medicine New York NY.
Background: Transport by mobile stroke units (MSUs), which provide access to computed tomography scanning and intravenous blood pressure medications and thrombolytics, reduces time to treatment and may improve short-term functional outcomes for patients with acute stroke. The longer-term clinical and financial impacts remain incompletely understood. The aim of the study was to determine whether MSU care is associated with better health, utilization, and spending outcomes for patients with suspected acute stroke.
View Article and Find Full Text PDFSci Rep
January 2025
North University of China, School of Mechanical Engineering, Taiyuan, 030051, Shanxi, China.
To improve the efficiency of mobile robot movement, this paper investigates the fusion of the A* algorithm with the Dynamic Window Approach (DWA) algorithm (IA-DWA) to quickly search for globally optimal collision-free paths and avoid unknown obstacles in time. First, the data from the odometer and the inertial measurement unit (IMU) are fused using the extended Kalman filter (EKF) to reduce the error caused by wheel slippage on the mobile robot's positioning and improve the mobile robot's positioning accuracy. Second, the prediction function, weight coefficients, search neighborhood, and path smoothing processing of the A* algorithm are optimally designed to incorporate the critical point information in the global path into the DWA calculation framework.
View Article and Find Full Text PDFJ Rheumatol
January 2025
P.F. Weiss, MD, MSCE, Department of Pediatrics, Division of Rheumatology and Clinical Futures, Children's Hospital of Philadelphia and Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Pennsylvania, USA.
Objective: To evaluate the influence of pelvic magnetic resonance imaging (MRI) findings on axial disease assessment in juvenile spondyloarthritis (JSpA).
Methods: This was a cross-sectional study of patients with JSpA with suspected axial disease. Three experts reviewed each case and rated their confidence (-3 to +3) in the presence of axial disease, first with clinical data and second with clinical and MRI data.
Environ Pollut
January 2025
Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.
Mobile air pollution measurements are typically aggregated by varying road segment lengths, grid cell sizes, and time intervals. How these spatiotemporal aggregation schemas affect the modeling performance of land use regression models has seldom been assessed. We used 5.
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