AI Article Synopsis
- - The study investigates how peer problems relate to ADHD symptoms, specifically focusing on the serotonin transporter gene, 5-HTTLPR, and its moderating role.
- - In a sample of 642 Norwegian children, results showed that only those with a specific gene variant (s-allele carriers) had more hyperactivity-impulsivity symptoms at age 6 based on peer problems reported by caregivers at age 4.
- - Similar findings were observed in a U.S. sample of 482 children, indicating that the impact of peer relations on ADHD symptoms can vary based on genetic sensitivity.
Article Abstract
Peer problems are linked to attention deficit hyperactivity disorder (ADHD) symptoms and the serotonin system is thought to be involved in ADHD-related behavior. Hence, from a Gene × Environment perspective, the serotonin transporter 5-HTTLPR may play a moderating role. In two large community samples, the moderating role of 5-HTTLPR was examined related to more hyperactivity-impulsivity symptoms (HI symptoms) predicted by more peer problems. In Study 1, involving 642 Norwegian children, results indicated that for s-allele carriers only, caregiver-reported peer problems at age 4 predicted more parent-reported HI symptoms at age 6. In Study 2, similar results emerged involving 482 American children. Discussion focuses on differential sensitivity to the adverse effects of poor peer relations.
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| http://dx.doi.org/10.1111/cdev.12766 | DOI Listing |
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