Unlabelled: Aim of the study was to elucidate value of HAS-BLED and HEMORR2HAGES scales for prediction bleedings in patients receiving long-term warfarin (W) therapy.
Material And Methods: The study involved 119 patients (72 men) aged 60.9+/-9.6 years with atrial fibrillation or venous thromboembolic complications. Follow up period was 5.6 +/-3.4 years. All bleedings were categorized as 1) single bleeding with INR>4.0 during the 1st month of W therapy; 2) any single bleeding after 1st month of W therapy; 3) recurrent bleedings. CYP29 and VKORC1 (G3673A) genotypic variants were determined by PCR. Patients were divided into low (<3 points of HAS-BLED scale, n=58; <4 points.
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Frailty Status Affects the Decision for Long-Term Anticoagulation Therapy in Elderly Patients with Atrial Fibrillation.
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Department of Internal Medicine, University Hospital of Heraklion "PAGNI", School of Medicine, University of Crete, Voutes, 71110, Heraklion, Crete, Greece.
Article Synopsis
- - The study aimed to evaluate anticoagulation therapy (AT) in elderly patients with atrial fibrillation (AF) and how frailty status impacts their long-term treatment outcomes.
- - Conducted in Greece with 104 patients aged 75 and older, the study found that 78.8% received AT at discharge; those not given AT had higher frailty and bleeding risk scores.
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Assessing the Appropriateness of Oral Anticoagulation for Atrial Fibrillation in Advanced Frailty: Use of Stroke and Bleeding Risk-Prediction Models.
J Frailty Aging
March 2018
Dr Rónán O'Caoimh, Centre for Gerontology and Rehabilitation, University College Cork, St Finbarrs Hospital, Douglas road, Cork City, Ireland, Email: Telephone: +353214901461, Facsimile: +3534901635.
Background: Atrial fibrillation (AF) is common among frail older adults. Oral anticoagulation (OAC) is particularly challenging for these due to overlapping stroke and bleeding risk factor profiles.
Objective: To compare the utility of stroke and haemorrhage risk-prediction instruments in the treatment of AF among frail older adults.
Unlabelled: Aim of the study was to elucidate value of HAS-BLED and HEMORR2HAGES scales for prediction bleedings in patients receiving long-term warfarin (W) therapy.
Material And Methods: The study involved 119 patients (72 men) aged 60.9 ± 9.
Unlabelled: Aim of the study was to elucidate value of HAS-BLED and HEMORR2HAGES scales for prediction bleedings in patients receiving long-term warfarin (W) therapy.
Material And Methods: The study involved 119 patients (72 men) aged 60.9+/-9.
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