Glandular Odontogenic Cyst is a relatively rare cyst of odontogenic origin, which shows glandular or salivary features that are thought to indicate the pluripotentiality of odontogenic epithelium. It is seen in middle-aged adults, and commonly involves the anterior region of the jaws, especially the mandible. It shows non-specific clinico-radiographic findings which may resemble other lesions, but has characteristic histopathologic features which help in its diagnosis. This paper reports an unusual presentation of a glandular odontogenic cyst which was diagnosed in a 64-year old female in the posterior maxilla, along with a literature review of this cyst, especially the cases reported in India in the past.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325494 | PMC |
| http://dx.doi.org/10.11604/pamj.2016.25.116.10879 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Are hypoxia-related proteins associated with the invasiveness of glandular odontogenic cysts? A multicenter study.
Arch Oral Biol
November 2024
Laboratory of Histopathology and Immunohistochemistry, School of Dentistry, Universidade Federal do Pará, Belém, Pará, Brazil. Electronic address:
Objective: The study aimed to investigate the expression of hypoxia markers associated with invadopodia in glandular odontogenic cysts and to explore an association between this expression with the aggressive biological behaviour of this odontogenic cyst.
Design: Immunohistochemistry was employed to assess the expression of hypoxia-inducible factor 1 alpha (HIF-1α), notch homologous protein of the neurogenic locus 1 (NOTCH-1), disintegrin and metalloproteinase-12 (ADAM-12), and heparin-binding epidermal growth factor (HB-EGF) in 17 samples of glandular odontogenic cysts, 10 samples of calcifying odontogenic cysts, and 10 samples of dental follicles.
Results: The glandular odontogenic cyst samples exhibited increased expression of HIF-1α, NOTCH-1, ADAM-12 and HBEGF proteins compared with calcifying odontogenic cyst and dental follicle samples.
Transformation of a Glandular Odontogenic Cyst into an Ameloblastoma: A Uncommon Phenomenon with a Review of Documented Cases.
Indian J Otolaryngol Head Neck Surg
December 2024
Department of Oral Medicine and Radiology, Government Dental College and Hospital, Srinagar, India.
Glandular odontogenic cysts(GOC) are among the rarest odontogenic cysts defined by the presence of glandular epithelium in the epithelial lining posing some diagnostic difficulties. GOC associated with ameloblastoma is extremely rare with only 5 cases reported. This report deals with this rare occurrence of GOC along with unicystic ameloblastoma.
View Article and Find Full Text PDFThe aim of this study was to evaluate the histopathologic diagnoses and radiographic characteristics of lesions associated with impacted teeth. In this retrospective study, 2624 biopsy reports were assessed. If the report was a record of a pericoronal lesion, the age and sex of the patient and the location, microscopic diagnosis, radiographic features, and size of the lesion were recorded.
View Article and Find Full Text PDFRare Histologic Imitator Central Mucoepidermoid Carcinoma Arising from Glandular Odontogenic Cyst of the Mandible: Case Report with Updated Review of Literature.
Indian J Otolaryngol Head Neck Surg
October 2024
Department of Oral Radiology, Maulana Azad Institute of Dental Sciences, Delhi, India.
Central mucoepidermoid carcinoma is a relatively rare salivary gland tumour of the jawbone. Glandular odontogenic cyst is another unique odontogenic developmental cyst characterised by glandular differentiation. Both entities share several histological characteristics, and a pre-existing Glandular odontogenic cyst can evolve into Central mucoepidermoid carcinoma.
View Article and Find Full Text PDFGlandular odontogenic cyst misdiagnosed and treated as a periapical inflammatory lesion for 6 years in an older adult.
Gerodontology
September 2024
Department of Pathology, School of Dentistry, Universidade de São Paulo, São Paulo, Brazil.
Article Synopsis
- The case involves a 76-year-old male who received multiple endodontic treatments for a misdiagnosed glandular odontogenic cyst, which was initially mistaken for an inflammatory periapical lesion.
- Glandular odontogenic cysts are known to be more aggressive compared to other types, and there's a lack of extensive research on this in older dental patients.
- The correct diagnosis was confirmed through a biopsy, leading to successful surgery while ensuring the base of the mandible was preserved, emphasizing the need for careful diagnosis in elderly patients.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!