[Functional examinations of visual channels: physiological basis].

Vestn Oftalmol

Moscow Helmholtz Research Institute of Eye Diseases, Ministry of Health of the Russian Federation, 14/19 Sadovaya-Chernogryazskaya St., Moscow, Russian Federation, 105062.

Published: July 2017

In this paper, technical details of visual evoked potentials (VEP) assessment and pattern electroretinography (PERG) are reviewed. Both methods are used to perform an objective functional examination of visual channels and to clarify the level, at which they have been damaged. Contributions of parvo- (P), magno- (M) and koniocellular (K) systems to the morphology of PERG and VEP responses are discussed with account to test conditions, selectively supportive of the activity of particular cell populations. The review analyzes the physiological role of such stimulation parameters as brightness and color contrast of the pattern elements as well as spatial and temporal frequency in detecting dysfunction of color channels and mistuning of the P- and M- pathways. Different times taken for neuronal integration and signal conduction along the M- and P- pathways determine the timing of the P- and M- VEP components, allowing us to judge their contribution to VEP morphology from the same recording.

Download full-text PDF

Source
http://dx.doi.org/10.17116/oftalma2017133197-102DOI Listing

Publication Analysis

Top Keywords

visual channels
8
[functional examinations
4
examinations visual
4
channels physiological
4
physiological basis]
4
basis] paper
4
paper technical
4
technical details
4
details visual
4
visual evoked
4

Similar Publications

Acupressure intervention for children: A scoping review.

Belitung Nurs J

January 2025

Doctorate Program of Medical and Health Science, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.

Background: Acupressure is a popular form of complementary nursing among adults. It stimulates the body's self-healing processes by enhancing energy flow, or "chi," along meridian channels. Acupressure can address many health issues and is also used on children because it is painless and straightforward.

View Article and Find Full Text PDF

Three-dimensional (3D) light-field displays can provide natural stereoscopic visual perception and an intuitive viewing experience. However, the high production threshold and the lack of user-friendly editing tools for light-field images make it difficult to efficiently and conveniently generate 3D light-field content that meets various needs. Here, a text-driven light-field content editing method for 3D light-field display based on Gaussian splatting is presented.

View Article and Find Full Text PDF

hERGAT: predicting hERG blockers using graph attention mechanism through atom- and molecule-level interaction analyses.

J Cheminform

January 2025

Department of Intelligent Electronics and Computer Engineering, Chonnam National University, Gwangju, Republic of Korea.

The human ether-a-go-go-related gene (hERG) channel plays a critical role in the electrical activity of the heart, and its blockers can cause serious cardiotoxic effects. Thus, screening for hERG channel blockers is a crucial step in the drug development process. Many in silico models have been developed to predict hERG blockers, which can efficiently save time and resources.

View Article and Find Full Text PDF

Selective activation of mesoscale functional circuits via multichannel infrared stimulation of cortical columns in ultra-high-field 7T MRI.

Cell Rep Methods

January 2025

Department of Neurosurgery of the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310029, China; Interdisciplinary Institute of Neuroscience and Technology, School of Medicine, Zhejiang University, Hangzhou 310029, China; National Key Laboratory of Brain and Computer Intelligence, Zhejiang University, Hangzhou 310058, China; Key Laboratory for Biomedical Engineering of Ministry of Education, College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou 310027, China; MOE Frontier Science Center for Brain Science and Brain-Machine Integration, School of Brain Science and Brain Medicine, Zhejiang University, Hangzhou 310012, China. Electronic address:

To restore vision in the blind, advances in visual cortical prosthetics (VCPs) have offered high-channel-count electrical interfaces. Here, we design a 100-fiber optical bundle interface apposed to known feature-specific (color, shape, motion, and depth) functional columns that populate the visual cortex in humans, primates, and cats. Based on a non-viral optical stimulation method (INS, infrared neural stimulation; 1,875 nm), it can deliver dynamic patterns of stimulation, is non-penetrating and non-damaging to tissue, and is movable and removable.

View Article and Find Full Text PDF

Background: Multifunctional fluorescent probes have attracted much attention due to their wide range of applications and high utilization. In this study, a multifunctional fluorescent probe (E)-3-(4-(7-(4-(diphenylamino)phenyl)benzo[c] [1,2,5]thiadiazol-4-yl)phenyl)acrylic acid (TBAC) based on triphenylamine was designed and synthesized.

Results: The TBAC probe provided excellent aggregation-induced emission (AIE) performance and could be used as a fluorescent ink for printing.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!