A Cu/PPh-catalyzed propargylic substitution reaction of diborylmethane is reported. Different substituted propargyl electrophiles can be employed in this reaction, and various synthetic valuable functional groups can be tolerated. Di-deuterated diborylmethane can also be used under these conditions and generates α-deuterated alkylboronic esters in good yield.
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| http://dx.doi.org/10.1039/c7cc00129k | DOI Listing |
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