Influence of Synbiotics on Selected Oxidative Stress Parameters.

The aim of the present study was to assess synbiotic ( + inulin) influence on oxidative stress parameters such as concentrations of malondialdehyde (MDA), hydrogen peroxide (HO), glutathione, and free sulfhydryl groups content. Experiments were carried out on healthy volunteers ( = 32). The subjects were divided into women group ( = 16) and men group ( = 16) and randomly assigned to synbiotic and control groups. Blood samples were collected before synbiotic supplementation and after 7 wks, at the end of the study. The administration of synbiotic resulted in a significant decrease in MDA ( < 0.01), HO ( < 0.01), and GSSG concentrations ( < 0.05) as compared with the control groups and significant increase in the concentrations of GSHt ( < 0.001), GSH ( < 0.01), and -SH group content ( < 0.05) versus control. Synbiotics containing plus inulin may have positive influence on selected oxidative stress markers.