AI Article Synopsis
- There is an inverse relationship between blood pressure and prognosis in heart failure (HF), which this study aims to clarify in a diverse group of patients.
- The study included 221 patients, primarily elderly, and found that those with lower systolic blood pressure (SBP) had higher mortality rates, while diastolic blood pressure (DBP) did not significantly affect outcomes.
- The research concludes that higher SBP at hospital admission is linked to lower all-cause mortality in HF patients, and this relationship is not significantly altered by the type of drug treatment they receive.*
Article Abstract
Background And Objective: An inverse relationship has been described between blood pressure and the prognosis in heart failure (HF). The characteristics of this relationship are not well unknown. The objective of this study was to determine if this relationship is maintained in a non-selected cohort of patients with HF and if it can be modified by treatment.
Material And Methods: Prospective study of cohorts including patients hospitalized for decompensated HF in Internal Medicine departments and followed as outpatients in a monographic consultation. Patients were classified according to their levels of systolic (SBP) and diastolic blood pressure (DBP). Clinical characteristics, all-cause mortality and readmissions after the first, third and sixth month of follow-up were analysed.
Results: Two hundred and twenty-one patients were included after their admission to the hospital for acute HF. Mean patient age was 79.5 years(SD 8.09); 115 patients were male. No significant differences between SBP quartiles and basal characteristics were found. Patients with lower SBP (Q1) had higher mortality rates (20%, P<.05). No significant differences between mortality/readmissions and DBP were found. However, the Kaplan-Meier analysis showed higher all-cause mortality rates for the group of patients with lower SBP and DBP (log-rank=0.011 and 0.041, respectively). The pharmacological treatment did not differ significantly between both study groups.
Conclusion: For non-selected patients suffering HF, higher SBP upon the admission is associated with significantly lower all-cause mortality rates during follow-up. Pharmacological treatment of HF does not seem to influence this inverse relationship between SBP at admission and patient mortality.
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| http://dx.doi.org/10.1016/j.medcli.2017.01.028 | DOI Listing |
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