New naphthalene derivative from the leaves of Cassia grandis L.

Nat Prod Res

d Department of Pharmaceutical Biochemistry, Institute of Applied Materials Science, Vietnam Academy of Science and Technology , Ho Chi Minh City , Vietnam.

Published: August 2017

Cassia grandis is used for the treatment of skin disorders, back pain, aches, etc. in Vietnamese traditional medicine. In this paper, phytochemicals of the leaves were investigated. A new naphthalene derivative (1, cassgranon D) and, seven known compounds rutin (2), afzelin (3), quercitrin (4), epicatechin (5), (-)-epiafzelechin (6), isoquercitrin (7) and aloe emodin (8) were isolated from the ethyl acetate and methanol extracts. Their structures were elucidated by spectral evidences (UV, IR, MS, H, C, DEPT, HSQC and HMBC NMR), as well as by comparing with published data.

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http://dx.doi.org/10.1080/14786419.2017.1290615DOI Listing

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